Results 131 to 140 of about 882,157 (403)

Association of Factor V Secretion with Protein Kinase B Signaling in Platelets from Horses with Atypical Equine Thrombasthenia. [PDF]

open access: yes, 2015
BackgroundTwo congenital bleeding diatheses have been identified in Thoroughbred horses: Glanzmann thrombasthenia (GT) and a second, novel diathesis associated with abnormal platelet function in response to collagen and thrombin stimulation.Hypothesis ...
Blevins, G   +4 more
core   +1 more source

The “Chestnuts” of the Horse [PDF]

open access: yesNature, 1902
THESE structures are well known and have been variously interpreted. But I believe that a suggestion as to their nature which I shall now put forward has not yet been made. Some months since I called attention in this Journal (vol. lxii. p. 523) to the general prevalence among mammals that use their fore limbs as grasping or climbing organs—in fact, in
openaire   +2 more sources

Characterization of the fecal bacteria communities of forage-fed horses by pyrosequencing of 16S rRNA V4 gene amplicons.

open access: yesFEMS Microbiology Letters, 2012
The diversity of the equine fecal bacterial community was evaluated using pyrosequencing of 16S rRNA gene amplicons. Fecal samples were obtained from horses fed cool-season grass hay.
M. Shepherd   +3 more
semanticscholar   +1 more source

Tumor‐Associated Sympathetic Nerves Promote the Progression of Epstein‐Barr Virus‐Positive Diffuse Large B‐Cell Lymphoma

open access: yesAdvanced Science, EarlyView.
Sympathetic nerve innervation promotes the progression of Epstein‐Barr virus‐positive diffuse large B‐cell lymphoma (EBV+ DLBCL) via β2‐adrenergic receptors. The discovery of enhanced nerve infiltration and β2AR expression reveals a novel mechanism and highlights the sympathetic–β2AR axis as a promising target for therapeutic intervention in EBV+ DLBCL.
Silan Huang   +10 more
wiley   +1 more source

Pyrosequencing of 16S rRNA genes in fecal samples reveals high diversity of hindgut microflora in horses and potential links to chronic laminitis

open access: yesBMC Veterinary Research, 2012
BackgroundThe nutrition and health of horses is closely tied to their gastrointestinal microflora. Gut bacteria break down plant structural carbohydrates and produce volatile fatty acids, which are a major source of energy for horses.
S. Steelman   +4 more
semanticscholar   +1 more source

Enhanced Media Optimize Bovine Myogenesis in 2D and 3D Models for Cultivated Meat Applications

open access: yesAdvanced Science, EarlyView.
This study uses multiomics approaches to characterize bovine myogenesis in vitro, identifying media components that enhance myogenic progenitor cell differentiation in 2D and 3D models. Notably, the enhanced conditions promoted formation of unique cell populations and contractile muscle cells expressing mature myogenic markers.
Christine L. Trautmann   +4 more
wiley   +1 more source

Pneumonia Caused by Klebsiella spp. in 46 Horses. [PDF]

open access: yes, 2015
BackgroundKlebsiella spp. are implicated as a common cause of bacterial pneumonia in horses, but few reports describe clinical presentation and disease progression.Hypothesis/objectivesTo describe the signalment, clinicopathologic data, radiographic and ...
Aleman, M   +7 more
core   +1 more source

Mutations in MITF and PAX3 Cause “Splashed White” and Other White Spotting Phenotypes in Horses

open access: yesPLoS Genetics, 2012
During fetal development neural-crest-derived melanoblasts migrate across the entire body surface and differentiate into melanocytes, the pigment-producing cells. Alterations in this precisely regulated process can lead to white spotting patterns.
Regula Hauswirth   +19 more
semanticscholar   +1 more source

Dynein‐Dependent Endo‐Lysosomal Degradation Drives Lewy Body Disorders Accompanied by Aβ Pathology

open access: yesAdvanced Science, EarlyView.
This study investigates the impact of Aβ plaques on α‐synuclein (αSyn) pathologies in dementia with Lewy bodies (DLB). Co‐culturing primary neurons with AD mouse brain slices reveals impaired dynein‐dependent organelle trafficking, affecting αSyn degradation. Activating Rab7 restores this process, reducing αSyn inclusions.
Linlin Zhou   +14 more
wiley   +1 more source

A genome-wide association study demonstrates significant genetic variation for fracture risk in Thoroughbred racehorses [PDF]

open access: yes, 2014
Background: Thoroughbred racehorses are subject to non-traumatic distal limb bone fractures that occur during racing and exercise. Susceptibility to fracture may be due to underlying disturbances in bone metabolism which have a genetic cause.
Blott, Sarah C.   +8 more
core   +4 more sources

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