Results 141 to 150 of about 882,157 (403)

Towards an Ethological Animal Model of Depression? A Study on Horses

open access: yesPLoS ONE, 2012
Background Recent reviews question current animal models of depression and emphasise the need for ethological models of mood disorders based on animals living under natural conditions.
C. Fureix   +4 more
semanticscholar   +1 more source

Disruption of ARID1B Recruitment to the Nuclear Pore Complex as a New Anticancer Therapeutic Strategy

open access: yesAdvanced Science, EarlyView.
This study identifies ARID1B as a chromatin‐bound driver of tumor growth in TNBC. ARID1B impairs ARID1A function and directly activates oncogenic programs through SWI/SNF remodeling. Its nuclear localization, mediated by the KPNA2–KPNB1–RANBP2 import machinery, is essential for its tumor‐promoting activity.
Olena Odnokoz   +14 more
wiley   +1 more source

Obesity prevalence and associated risk factors in outdoor living domestic horses and ponies [PDF]

open access: yes, 2014
Reasons for performing study. The prevalence of obesity in companion animals, including horses and ponies has risen drastically in recent years and risk factors have been little investigated.
Giles, Sarah L   +3 more
core   +2 more sources

Prevalence of overconditioning in mature horses in southwest Virginia during the summer.

open access: yesJournal of Veterinary Internal Medicine, 2012
BACKGROUND The prevalence of obesity in horses in the eastern United States is not well documented. OBJECTIVE To determine body condition and risk factors for obesity in horses in Southwest Virginia during summer. ANIMALS A sample of 300 mature (4-20
C. Thatcher   +3 more
semanticscholar   +1 more source

Mechanical Forces Guide Axon Growth through the Nigrostriatal Pathway in an Organotypic Model

open access: yesAdvanced Science, EarlyView.
Nano‐pulling is a magnetic nanoparticle‐based technology for guiding and promoting the axon growth of induced pluripotent stem cell‐derived dopaminergic neurospheres in vitro or neural progenitors transplanted in the brain tissue. Fine control of axon guidance is essential for reconstructing neural networks and restoring functional connectivity in the ...
Sara De Vincentiis   +7 more
wiley   +1 more source

Metalloproteinases and their Inhibitors under the Course of Immunostimulation by CPG-ODN and Specific Antigen Inhalation in Equine Asthma [PDF]

open access: yes, 2019
Objectives. Inhalation of immunostimulatory bacterial DNA segments (cytosine-phosphate-guanosine-oligodeoxynucleotides, CpG-ODN) normalizes clinical and cytologic parameters in severe equine asthma.
Barton, Ann Kristin   +5 more
core   +1 more source

Extracellular LCN2 Binding to 24p3R in Astrocytes Impedes α‐Synuclein Endocytosis in Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
24p3R is an astrocytic receptor for α‐Syn uptake. When LCN2 is secreted from astrocytes, it binds to its receptor 24p3R in astrocytes and this binding impedes the α‐Syn PFF binding to 24p3R. This in turn inhibits 24p3R‐mediated α‐Syn PFF uptake and reduces the clearance of extracellular α‐Syn by astrocytes, which contributes to α‐Syn spread and ...
Ying‐Ying Jiao   +14 more
wiley   +1 more source

Transportation in McMinnville 100 Years Ago [PDF]

open access: yes, 2012
Our project presents a historical view of transportation and its development in McMinnville in the 1910s, especially in 1912. McMinnville was incorporated as a town in 1876 and became a city in 1882.
Derby, Justin   +2 more
core   +1 more source

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