Advanced Science, EarlyView.A theranostic nanoplatform is formulated with NIR‐II emissive lipophilic cyanine dye IRC18 to intercalate into genetically engineered IL12/CSF1R‐macrophage membrane‐liposome hybrid nanovesicles, which assists to achieve blood–brain barrier crossing, glioblastoma targeting, NIR‐II fluorescence imaging, image‐guided membrane‐targeted mild photothermal ...
Pengfei Chen +10 more
wiley +1 more source
Vertical movement symmetry of the withers in horses with induced forelimb and hindlimb lameness at trot [PDF]
, 2018 Background The main criteria for lameness assessment in horses are head movement for forelimb lameness and pelvic movement for hindlimb lameness. However, compensatory head nod in horses with primary hindlimb lameness is a well‐known phenomenon.
Arkell +20 more
core +3 more sources
Mutations in MITF and PAX3 Cause “Splashed White” and Other White Spotting Phenotypes in Horses
PLoS Genetics, 2012 During fetal development neural-crest-derived melanoblasts migrate across the entire body surface and differentiate into melanocytes, the pigment-producing cells. Alterations in this precisely regulated process can lead to white spotting patterns.
Regula Hauswirth +19 more
semanticscholar +1 more source
Mechanical Forces Guide Axon Growth through the Nigrostriatal Pathway in an Organotypic Model
Advanced Science, EarlyView.Nano‐pulling is a magnetic nanoparticle‐based technology for guiding and promoting the axon growth of induced pluripotent stem cell‐derived dopaminergic neurospheres in vitro or neural progenitors transplanted in the brain tissue. Fine control of axon guidance is essential for reconstructing neural networks and restoring functional connectivity in the ...
Sara De Vincentiis +7 more
wiley +1 more source
Towards an Ethological Animal Model of Depression? A Study on Horses
PLoS ONE, 2012 Background Recent reviews question current animal models of depression and emphasise the need for ethological models of mood disorders based on animals living under natural conditions.
C. Fureix +4 more
semanticscholar +1 more source
Dipyridamole Acts as Clinical Ferroptosis Inhibitor to Prevent from Tissue Injury
Advanced Science, EarlyView.Dipyridamole acts as a clinically used compound to suppress ferroptosis. Dipyridamole down‐regulates the expression of RNF126, which is an E3 ligase to ubiquitinate SLC7A11 for proteasome degradation. The deficiency of SLC7A11 largely abolishes the protective role of dipyridamole both in vitro and in vivo.
Xiao Zhuang +22 more
wiley +1 more source
Correlation between capillary oxygen saturation and small intestinal wall thickness in the equine colic patient [PDF]
, 2017 The surgical evaluation of haemorrhagic infarcted intestine and the decision for or against bowel resection require a lot of experience and are subjective.
Kunzmann, Robert +4 more
core +1 more source
scCompass: An Integrated Multi‐Species scRNA‐seq Database for AI‐Ready
Advanced Science, EarlyView.scCompass integrates and standardizes transcriptomic data from ≈105 million single cells across 13 species, enabling the identification of stable expression genes and organ‐specific expression genes in humans and mice. It provides scalable datasets for AI model training, pretrained model checkpoints, and user‐friendly platforms for data sharing ...
Pengfei Wang +29 more
wiley +1 more source
LXVII.—On the Preorbital Pit in the Skulls of Domestic Horses and Quaggas [PDF]
, 1905 R.I. Pocock
openalex +1 more source
A retinoscopic survey of 333 horses and ponies in the UK [PDF]
, 2014 Introduction: Ophthalmic examination in the horse is generally limited to crude assessment of vision and screening for ocular lesions. The refractive state of equine eyes and the potential impact on vision and performance requires further ...
Chung +38 more
core +1 more source