Results 181 to 190 of about 893,278 (399)

A Serum‐Stable Antimicrobial Peptide‐Based Delivery Platform for Selective Treatment of Nontargetable and Chemoresistant Tumors

open access: yesAdvanced Science, EarlyView.
A modular antimicrobial‐peptide‐based therapeutic system integrating membrane‐targeted selectivity, a conformation‐driven polyethylene glycolylated blocker, and serum‐stabilizing N‐cap is developed. The optimized conjugate 270 shows potent, rapid killing of the desired tumor cells, high serum stability, low off‐target toxicity, and broad applicability,
Tianxing Liu   +12 more
wiley   +1 more source

Preliminary report of the committee appointed to examine into the modes of determining the horse-power of steam-boilers [PDF]

open access: green, 1871
Edward L. Brown   +4 more
openalex   +1 more source

Horses and Mules: 1945 Illinois Agricultural Statistics [PDF]

open access: yes, 1946
Number and total value of Illinois horses and mules by county, district, and state in 1945 and 1946.published or submitted for publicationnot peer ...

core  

Norepinephrine Induces Sertoli Cell Ferroptosis via Receptors Desensitization Causing Stress‐Related Male Reproductive Dysfunction

open access: yesAdvanced Science, EarlyView.
Psychological stress activates the sympathetic–adrenal axis, elevating norepinephrine (NE) and suppressing reproductive hormones, thereby impairing male reproduction. Excess NE overactivates and desensitizes β‐adrenergic receptors (β‐ARs), triggering Sertoli cell ferroptosis and disrupting spermatogenesis.
Lingyu Zhang   +12 more
wiley   +1 more source

Development, refinement, and validation of an equine musculoskeletal pain scale

open access: yesFrontiers in Pain Research
Musculoskeletal disease is a common cause of chronic pain that is often overlooked and inadequately treated, impacting the quality of life of humans and horses alike. Lameness due to musculoskeletal pain is prevalent in horses, but the perception of pain
Ulrike Auer   +8 more
doaj   +1 more source

The Sense of “Horse” in Horse Latitudes

open access: yesJournal of Geography, 1967
(1967). The Sense of “Horse” in Horse Latitudes. Journal of Geography: Vol. 66, No. 7, pp. 385-387.
openaire   +2 more sources

One‐Step Drug Screening System Utilizing Electrophysiological Activity in Multiple Brain Organoids

open access: yesAdvanced Science, EarlyView.
This study presents a one‐step system that delivers different drug doses to brain organoids and monitors their neural activity using integrated 3D microelectrodes. By combining dose‐specific microfluidic delivery with high‐resolution electrophysiological recording, the platform enables simultaneous, real‐time screening of neural responses across ...
Hyogeun Shin   +9 more
wiley   +1 more source

SIRT6 Lysine‐Demyristoylates ATF2 to Ameliorate Vascular Injury via PRKCD/VE‐Cadherin Pathway Regulating Vascular Endothelial Barrier

open access: yesAdvanced Science, EarlyView.
A novel modified SIRT6 variant (dSIRT6) H133Y‐mediated enrichment technique unmasks 15 new human lysine‐myristoylated proteins. Notably, Sirtuin 6 (SIRT6) demyristoylation of activating transcription factor 2 (ATF2) at K296 orchestrates its nucleoplasmic translocation.
Runyang Feng   +40 more
wiley   +1 more source

Show Quality Quarter Horse Auctions: Price Determinants and Buy-Back Practices [PDF]

open access: yes
This study estimates the price determinants of show quality quarter horses sold at auction. Several characteristics including genetic and physical traits, quality of pedigree, and performance record of the horse, as well as the horse's offspring, were ...
Dhuyvetter, Kevin C.   +4 more
core   +1 more source

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