Results 251 to 260 of about 721,045 (358)

A Meta‐Analysis of International Flunixin Pharmacokinetics in Horses: Toward Regulatory Harmonization and Individualized Detection Times Using Bayesian Paradigm

open access: yesDrug Testing and Analysis, EarlyView.
A meta‐analysis of flunixin concentrations in 65 horses from four countries estimated pharmacokinetic parameters. Considering the estimated plasma‐to‐urine ratio, raising the plasma International Screening Limit (ISL) from 1 to 3 ng/mL while keeping the urine ISL at 100 ng/mL could reduce the difference in detection times between the two matrices ...
Taisuke Kuroda   +9 more
wiley   +1 more source

LITHOTOMY ON THE HORSE.

open access: green
Thomas Bidwell, Edward Randell
openalex   +2 more sources

Metformin in the Horse: Pharmacokinetics and Detection Times Using Monte Carlo Simulations

open access: yesDrug Testing and Analysis, EarlyView.
In recent years, the detection of metformin in blood and urine samples collected from racehorses has raised concern among regulators. This study describes blood and urine concentrations and the pharmacokinetics of metformin following IV and oral administration to horses. Data presented here can be used to establish screening limits and withdrawal times
Megan E. Jacobs   +5 more
wiley   +1 more source

Improvement of EPO Transgene Detection From Polymeric Dried Blood Spots for Antidoping Application

open access: yesDrug Testing and Analysis, EarlyView.
This article presents an optimized protocol for gene doping detection. Starting from one spot DBS (20 μL), concentrated DNA was obtained and real‐time PCR parameters were adjusted for increased detection. Robust detection of 5000 copies/mL of transgene was validated for polymeric device TASSO M‐20.
Alexandre Marchand   +2 more
wiley   +1 more source

Hotspots, trends, and regional focus on oil or gas exploration: A bibliometric comparative study

open access: yesDeep Underground Science and Engineering, EarlyView.
This paper explores the research trends in global oil and gas exploration through the bibliometric analysis of 3460 articles collected from the Web of Science database on oil and gas exploration published from 2013 to 2023. The research hotspots, objects, regional distribution, methods, and evaluation methods of oil and gas exploration are analyzed and
Jihong Wang   +3 more
wiley   +1 more source

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