Results 1 to 10 of about 23,206 (98)

Oligosaccharide feed supplementation reduces plasma insulin in geldings with Equine Metabolic Syndrome [PDF]

Frontiers in Microbiomes, 2023
BackgroundThe prevalence of Equine Metabolic Syndrome and insulin dysregulation is increasing in the horse population. Insulin dysregulation is a risk factor for laminitis, which has significant welfare consequences for the horse.
Alexandra von Münchow, Alexandra von Münchow, Sarah Torp Yttergren, Rasmus Riemer Jakobsen, Nanna Luthersson, Axel Kornerup Hansen, Frederikke Lindenberg   +6 more
doaj   +4 more sources

Clustering and Correlations amongst NEFA, Selected Adipokines and Morphological Traits—New Insights into Equine Metabolic Syndrome [PDF]

Animals, 2022
Obesity is a common feature in horses suffering from metabolic syndrome. While adipokines involvement as biomarkers is better established in human pathology, little data are available on horses.
Zsofia Daradics, Mihaela Niculae, Cristian Mihăiță Crecan, Alexandru Florin Lupșan, Mirela Alexandra Rus, Sanda Andrei, Dana Mihaela Ciobanu, Florinela Adriana Cătoi, Ioana Delia Pop, Mircea Valerian Mircean, Cornel Cătoi   +10 more
doaj   +2 more sources

Astaxanthin Carotenoid Modulates Oxidative Stress in Adipose-Derived Stromal Cells Isolated from Equine Metabolic Syndrome Affected Horses by Targeting Mitochondrial Biogenesis [PDF]

Biomolecules, 2022
Astaxanthin is gaining recognition as a natural bioactive component. This study aimed to test whether astaxanthin could protect adipose-derived stromal stem cells (ASCs) from apoptosis, mitochondrial dysfunction and oxidative stress.
Malwina Mularczyk, Nabila Bourebaba, Krzysztof Marycz, Lynda Bourebaba   +3 more
doaj   +2 more sources

Quantitative proteomics unveils potential plasma biomarkers and provides insights into the pathophysiological mechanisms underlying equine metabolic syndrome [PDF]

BMC Veterinary Research
Background Equine Metabolic Syndrome (EMS) is a multifactorial endocrine disorder characterized by obesity, insulin dysregulation (ID), and an increase in the risk of laminitis, a painful condition that can lead to euthanasia in severe cases.
E. M. Espinosa-López, B. Ortiz-Guisado, E. Diez de Castro, A. Durham, E. Aguilera-Tejero, G. Gómez-Baena   +5 more
doaj   +2 more sources

From Diet to Disease: The Role of the Gut Microbiome and Microbial Metabolites in Horses [PDF]

Veterinary Sciences
The equine gastrointestinal microbiome plays an essential role in digestion, energy metabolism, immune regulation, and maintenance of intestinal homeostasis.
Yuhong Wu, Yuhui Ma, Yiyi Zan, Xu Bai, Jing Li, Hai Li   +5 more
doaj   +2 more sources

Spirulina platensis Improves Mitochondrial Function Impaired by Elevated Oxidative Stress in Adipose-Derived Mesenchymal Stromal Cells (ASCs) and Intestinal Epithelial Cells (IECs), and Enhances Insulin Sensitivity in Equine Metabolic Syndrome (EMS) Horses

Marine Drugs, 2017
Equine Metabolic Syndrome (EMS) is a steadily growing life-threatening endocrine disorder linked to insulin resistance, oxidative stress, and systemic inflammation.
Daria Nawrocka, Katarzyna Kornicka, Agnieszka Śmieszek, Krzysztof Marycz   +3 more
doaj   +3 more sources

The Role of Omega-3 Fatty Acids in Horses’ Nutrition—A Review [PDF]

Animals
This narrative review presents examples of omega-3 fatty acids supplementation in horse nutrition. Fats are essential in equine nutrition, serving not only as an energy source but also as functional components influencing health.
Julia Bronś, Katarzyna Czyż, Anna Wyrostek, Jakub Smoliński, Wojciech Kruszyński, Ewa Sokoła-Wysoczańska, Karolina Dorobisz   +6 more
doaj   +2 more sources

Faecal microbiota and serum metabolome association with equine metabolic syndrome in connemara ponies [PDF]

BMC Veterinary Research
Background Faecal microbiome and serum metabolome have been studied in human medicine to provide a better understanding of metabolic derangements including diabetes; however, equivalent studies in equine medicine are limited.
Ahmed Saleh Al-Ansari, Vivienne Duggan, Grace Mulcahy, Xiaofei Yin, Lorraine Brennan, Paul D. Cotter, Shriram H. Patel, Ciara M. O’Donovan, Fiona Crispie, Nicola Walshe   +9 more
doaj   +2 more sources

In Vivo Metabolite Formation and In Vitro Cytochrome P450-Mediated Metabolism of Vonoprazan in Horses [PDF]

Metabolites
Background/Objectives: Vonoprazan is a potassium-competitive acid blocker with potential for the treatment of equine gastric ulcer syndrome. Vonoprazan metabolic pathways in horses have not been characterized.
Camilo J. Morales, Daniel S. Mckemie, Jayanti Bhandari Neupane, Heather K. Knych   +3 more
doaj   +2 more sources

Metformin Increases Proliferative Activity and Viability of Multipotent Stromal Stem Cells Isolated from Adipose Tissue Derived from Horses with Equine Metabolic Syndrome [PDF]

Cells, 2019
In this study, we investigated the influence of metformin (MF) on proliferation and viability of adipose-derived stromal cells isolated from horses (EqASCs).
Agnieszka Smieszek, Katarzyna Kornicka, Jolanta Szłapka-Kosarzewska, Peter Androvic, Lukas Valihrach, Lucie Langerova, Eva Rohlova, Mikael Kubista, Krzysztof Marycz   +8 more
doaj   +2 more sources