Associations between endocrine disrupting chemicals and equine metabolic syndrome phenotypes. [PDF]
Chemosphere, 2019 Equine Metabolic Syndrome (EMS) is characterized by abnormalities in insulin regulation, increased adiposity and laminitis, and has several similarities to human metabolic syndrome. A large amount of environmental variability in the EMS phenotype is not explained by commonly measured factors (diet, exercise, and season), suggesting that other ...
Durward-Akhurst SA +9 more
europepmc +6 more sources
Marine Drugs, 2017 Equine Metabolic Syndrome (EMS) is a steadily growing life-threatening endocrine disorder linked to insulin resistance, oxidative stress, and systemic inflammation.
Daria Nawrocka +3 more
doaj +3 more sources
Equine metabolic syndrome in Colombian creole horse: case report [PDF]
Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2017 The equine metabolic syndrome is a condition that can be recognized because of obesity, insulin resistance and laminitis. Genetic factors could play a role in the occurrence of this syndrome.
C.A. Castillo +3 more
doaj +3 more sources
Metformin Increases Proliferative Activity and Viability of Multipotent Stromal Stem Cells Isolated from Adipose Tissue Derived from Horses with Equine Metabolic Syndrome [PDF]
Cells, 2019 In this study, we investigated the influence of metformin (MF) on proliferation and viability of adipose-derived stromal cells isolated from horses (EqASCs).
Agnieszka Smieszek +8 more
doaj +2 more sources
Faecal microbiota and serum metabolome association with equine metabolic syndrome in connemara ponies [PDF]
BMC Veterinary ResearchBackground Faecal microbiome and serum metabolome have been studied in human medicine to provide a better understanding of metabolic derangements including diabetes; however, equivalent studies in equine medicine are limited.
Ahmed Saleh Al-Ansari +9 more
doaj +2 more sources
Use of principle component analysis to quantitatively score the equine metabolic syndrome phenotype in an Arabian horse population. [PDF]
PLoS ONE, 2018 Equine metabolic syndrome (EMS), like human metabolic syndrome, comprises a collection of clinical signs related to obesity, insulin dysregulation and susceptibility to secondary inflammatory disease.
Samantha L Lewis +4 more
doaj +2 more sources
Laminitis and the Equine Metabolic Syndrome
Veterinary Clinics of North America: Equine Practice, 2010 Although much has been written about laminitis in the context of its association with inflammatory processes, recognition is growing that most cases of laminitis examined by veterinarians in private practice are those associated with pasture grazing, obesity, and insulin resistance (IR). The term 'endocrinopathic laminitis' has been adopted to classify
Philip J, Johnson +4 more
openaire +4 more sources
is equine disease comparable to what we know in humans? [PDF]
Endocrine Connections, 2014 This review summarizes similarities and differences between the metabolic syndromes in humans and equines, concerning the anatomy, symptoms, and pathophysiological mechanisms.
Barton, Ann Kristin +3 more
core +4 more sources
Advancing in vitro vascular wall modelling using digital light processing to study hyperglycemia-driven cell changes [PDF]
Frontiers in Bioengineering and BiotechnologyBackgroundMetabolic syndrome is a pathological state, frequently associated with type 2 diabetes, which is marked by abdominal obesity, impaired insulin action, hypertension, and vascular wall changes.
Ianina Pokholenko +8 more
doaj +2 more sources
Evaluation of Oxidative Stress and Mitophagy during Adipogenic Differentiation of Adipose-Derived Stem Cells Isolated from Equine Metabolic Syndrome (EMS) Horses [PDF]
Stem Cells International, 2018 Mesenchymal stem cells (MSCs) are frequently used in both human and veterinary medicine because their unique properties, such as modulating the immune response and differentiating into multiple lineages, make them a valuable tool in cell-based therapies.
Krzysztof Marycz +3 more
doaj +2 more sources