Results 151 to 160 of about 2,764 (222)
Advanced Science, Volume 13, Issue 14, 9 March 2026.This study demonstrates that HDAC1/2 knockout in microglia alleviates neurological deficits, preserves white matter, and accelerates hematoma clearance after ICH. HDAC1/2 inhibition reduces HK2 acetylation, shifts metabolism from glycolysis to fatty acid oxidation, reduces inflammation, and enhances phagocytosis.
Zhiwen Jiang +9 more
wiley +1 more source
Saúde sexual e reprodutiva de mulheres vivendo com HIV/AIDS atendidas em Hospital Dia
, 2014 Os dados da Organização Mundial da Saúde, bem como os nacionais, mostram o avanço da epidemia de aids entre as mulheres, com maior concentração de casos na faixa reprodutiva. O objetivo deste estudo foi analisar aspectos da saúde sexual e reprodutiva de mulheres infectadas pelo HIV/Aids atendidas no Serviço de Ambulatórios Especializados e Hospital Dia
openaire +1 more source
Ribosome Homeostasis Regulated by SETD2 Preserves Intestinal Epithelial Barrier
Advanced Science, Volume 13, Issue 16, 18 March 2026.SETD2 ablation causes dysregulation and recruitment defects of ribosome biogenesis factors, resulting in translational disorders of barrier maintenance genes, thereby compromising the intestinal barrier. These findings unveil a previously unappreciated role of ribosome biogenesis and translational regulation in preserving the intestinal epithelial ...
Hanyu Rao +11 more
wiley +1 more source
Estudo de Reuniões de Equipe Geral em um Hospital-Dia Psiquiátrico. [PDF]
, 2015 openaire +1 more source
RUNX2 Activation in Fibro/Adipogenic Progenitors Promotes Muscle Fibrosis in Muscular Dystrophy
Advanced Science, Volume 13, Issue 13, 3 March 2026.This study revealed a novel role of the chemokine‐TGF‐β1‐RUNX2 axis in determining the fate of FAP differentiation and modulating muscle fibrosis in patients and mice with muscular dystrophies. ABSTRACT Clinical evidence indicates concurrent muscle inflammation and fibrosis in muscular dystrophies (MDs); however, the molecular mechanisms underlying ...
Pengkai Wu +12 more
wiley +1 more source
Advanced Science, Volume 13, Issue 16, 18 March 2026.A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li +8 more
wiley +1 more source