Results 201 to 210 of about 2,764 (222)
Design, Synthesis, and Evaluation of Bis‐Chalcones and Bis‐Flavones as Selective COX‐2 Inhibitors
Chemical Biology &Drug Design, Volume 107, Issue 3, March 2026.Novel bis‐chalcones were successfully synthesized and demonstrated COX‐2 selective inhibition and the ability to inhibit PGE2 production in whole human blood. Notably, a monomeric chalcone with a similar substitution pattern exhibited even greater activity, providing valuable insights to guide the future design and optimization of flavonoid‐based COX‐2
Rui Pereira +4 more
wiley +1 more source
Child: Care, Health and Development, Volume 52, Issue 2, March 2026.ABSTRACT Background The rise of digital media has significantly altered how parents access information regarding child development and parenting. While such platforms provide accessible support, the influence of different media formats on parenting outcomes remains underexplored.
Pornnapasorn Nguansiri +6 more
wiley +1 more source
Child: Care, Health and Development, Volume 52, Issue 2, March 2026.ABSTRACT Background Violence experienced by women has serious consequences for maternal and child health, generating short‐ and long‐term damage. Objective The aim of this study was to evaluate the relation between violence experienced by women and the mother–child bond in the first 6 months after childbirth and on the child's mental health at ...
Viviane Costa de Souza Buriol +6 more
wiley +1 more source
Mechanism of ITGB2 in Osteoclast Differentiation in Osteoarthritis
Cell Proliferation, Volume 59, Issue 3, March 2026.In osteoclast precursors, higher ITGB1 than ITGB2 expression increases ITGA2‐ITGB1 integrin. In OA, extracellular signals upregulate ITGB2 and downregulate ITGB1, enhancing ITGA2‐ITGB2 integrin. This activates Rac1 to Rac‐GTP, driving osteoclast differentiation. Hyperactive subchondral osteoclasts accelerate OA progression.
Yang Yang +16 more
wiley +1 more source
Diabetic Medicine, Volume 43, Issue 3, March 2026.Abstract Aim Although hybrid closed‐loop systems (HCLS) and sensor‐augmented pump (SAP) therapy are advanced diabetes management technologies for type 1 diabetes, their relative efficacy in optimising glycaemic control is not fully established. This meta‐analysis evaluated the impact of HCLS versus SAP therapy on glucose regulation across multiple ...
Amardeep S. Sidki +3 more
wiley +1 more source
Perfil das gestantes com diabetes gestacional atendidas no hospital dia do HMIPV
, 2010 Pauline Soares Ferrugem
openalex +1 more source