Results 31 to 40 of about 2,764 (222)

Abordagem não farmacológica no controlo das náuseas e vómitos induzidos pela quimioterapia

Onco.News, 2008
As náuseas e vómitos são dos efeitos secundários mais referidos pelos doentes submetidos a tratamentos com quimioterapia. Estes assumem um impacto negativo na qualidade de vida dos doentes, na medida em que interferem nas actividades de vida diárias ...
Maria de Fátima Rodrigues Francisco
doaj   +1 more source

Is the pursuit of happiness the pursuit of homeostasis? A review on the modulatory functions of endorphins on human behavior

European Psychiatry, 2022
Introduction Endorphins have been associated with analgesia and pleasurable activities. However, the so-called “happy chemicals” are far more complex than initially thought. Research shows that their impact on human behavior is modulatory, with the main
M. Conde Moreno, F. Ramalheira
doaj   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Sharing is caring: a review on Oxytocin role in human behaviour and clinical implications

European Psychiatry, 2022
Introduction Oxytocin, also known as the love molecule, was discovered in 1906 because of its effects on uterine contractions. It exists in all mammals and is partly responsible for delivery.
F. Ramalheira, M. Conde Moreno
doaj   +1 more source

Psicoterapia de grupo de apoio multifamiliar (PGA) em hospital-dia (HD) psiquiátrico

Revista Brasileira de Psiquiatria, 1999
INTRODUÇÃO: O familiar é a ponte, entre o ambiente da casa do paciente e o ambiente terapêutico do hospital-dia (HD), onde o paciente permanece das 7h30 às 15h30, de segunda a sexta-feira. A complexidade para a integração do exercício dessa tarefa e suas conseqüências para o tratamento em HD, levou-nos a criar a Psicoterapia de Grupo de Apoio ...
Contel, José Onildo B., Villas-Boas, Maria Aparecida   +1 more
openaire   +4 more sources

Isolation Defines Identity: Functional Consequences of Extracellular Vesicle Purification Strategies

Advanced Healthcare Materials, EarlyView.
Four extracellular vesicle purification strategies are compared using ovarian‐cancer ascites and ES‐2 cell supernatants. A novel workflow links purification to function by combining particle‐normalized proteomics with matched cell‐free and cell‐based assays.
Christian Preußer, Dolores J. Salander, Witold Szymanski, Johannes Graumann, Yukai Wang, Kai Zhao, Jörg W. Bartsch, María Gómez‐Serrano, Daniel Bachurski, Silke Reinartz, Elke von Pogge von Strandmann   +10 more
wiley   +1 more source

3D Printed Multimaterial Microfluidic Transistors

Advanced Materials Technologies, EarlyView.
We introduce a biocompatible, high resolution photopolymer resin that closely mimics the Young's Modulus (elasticity) and reversible stretchability (no hysteresis) of poly(dimethylsiloxane) (PDMS), enabling the fabrication of microfluidic transistors (i.e., microvalves capable of proportional amplification) by multimaterial stereolithography (mSLA ...
Alireza Ahmadianyazdi, Wei Huang, Kaustav A. Gopinathan, Ivan Stepanov, Lisa Horowitz, Ting‐Yuan Tu, Mehmet Toner, Albert Folch   +7 more
wiley   +1 more source

Bufalin Inhibits the PI3K/AKT Pathway by Targeting GTF3C4 to Impede Breast Cancer Progression

Advanced Science, EarlyView.
Mechanisms of Bufalin‐Mediated Intervention in Breast Cancer. ABSTRACT Breast cancer incidence is rising globally, presenting challenges such as treatment side effects and drug resistance. Bufalin is a bufadienolides compound with potential anti‐cancer effects. This study shows that bufalin inhibits malignant proliferation of MDA‐MB‐231 and MCF‐7 cells
Siyu Guo, Xiaodong Chen, Haojia Wang, Jiying Zhou, Peiying Lu, Jiangying Liu, Keyan Chai, Jingyuan Zhang, Siyun Yang, Shan Lu, Yifei Gao, Zhengsen Jin, Xiaoyu Tao, Zhongdong Hu, Qinglin Li, Jiarui Wu   +15 more
wiley   +1 more source

Effectiveness of a digital diabetes self-management education and support program in Vietnamese adults with type 2 diabetes

Scientific Reports
Diabetes mellitus remains a major global public health challenge. Mobile applications and digital platforms offer innovative opportunities to enhance diabetes self-management.
Phong Vu Nhat Nguyen, Phola Thi Thach, Hoanh Kieu Tran, Ha Thi Hong Nguyen, Dai Lan Truong, Uyen Lam, Viet Quoc Tran, Nhi Y To, Nhat Tran Hoang Luong, Duong Thi Thai Le, Khanh Quang Tran, Luong Dai Ly   +11 more
doaj   +1 more source

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

Advanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang, Linghua Zeng, Kunkun Zou, Keying Lin, Fangting Yao, Jinglun Song, Shumeng Zhang, Hanshu Feng, Zhichao Yang, Chunlei Wang, Hongtao Diao, Xue Kong, Tengfei Pan, Joonki Kim, Tianqi Duo, Linqiang Li, Yu Bian   +16 more
wiley   +1 more source