Results 141 to 150 of about 12,173,986 (325)

Barnes Hospital Record [PDF]

open access: yes, 1953
https://digitalcommons.wustl.edu/bjc_barnes_record/1075/thumbnail ...

core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Conferencias Anatomopatológicas

open access: yesRevista de la Facultad de Medicina, 1953
Caso número cuatro: La enferma ingresa al servicio de Clínica Semiológica el 5 de abril de 1951, por presentar ictericia, fiebre, dolor abdominal intenso, localizado principalmente en el hipocondrio derecho, nauseas, vomitus y cefalea / Caso número cinco:
San Juan de Dios Hospital de
doaj  

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

THE COMBINATION OF BLOOD GROUPS IN A SAMPLE OF 475 PEOPLE IN A LONDON HOSPITAL [PDF]

open access: bronze, 1949
Doreen Bertinshaw   +4 more
openalex   +1 more source

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

open access: yesMolecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa   +14 more
wiley   +1 more source

13º Jornada do Serviço de Educação Física e Terapia Ocupacional

open access: yesClinical and Biomedical Research
A Jornada do Serviço de Educação Física e Terapia Ocupacional (SEFTO) do Hospital de Clínicas de Porto Alegre é um evento tradicional, que geralmente ocorre a cada 4 anos, que em razão da pandemia somente pode ser retomada em 2024.
Hospital de Clínicas de Porto Alegre
doaj   +2 more sources

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