ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren+8 more
wiley +1 more source
Evaluation of a virtual emergency care service to avoid unnecessary emergency department presentations and provide specialist-led definitive care. [PDF]
Joyce LR+6 more
europepmc +1 more source
Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu+6 more
wiley +1 more source
Atrial fibrillation patients presenting to an emergency department successfully managed with a next-day community follow-up pathway: A before-and-after cohort study. [PDF]
Brokenshire F+6 more
europepmc +1 more source
BRAIN TUMORS AS SEEN IN HOSPITALS FOR THE INSANE [PDF]
Mary Elizabeth Morse
openalex +1 more source
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley +1 more source
'I Have Never Been in That Kind of All-Consuming Pain … I Did Not Know What Else to Do': The Journey to Hospital Admission With Low Back Pain From the Perspectives of Patients. [PDF]
Orlando JF+4 more
europepmc +1 more source
Are EDs the Only Option? Hospital-Based Alternatives to the Emergency Department for Mental Health Crises: A Scoping Review. [PDF]
Hudson C, Bowman C, Randall M.
europepmc +1 more source