Results 191 to 200 of about 12,173,986 (325)

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Resuscitation outcomes and associated factors among out-of-hospital cardiac arrest patients at the National Referral Hospital, Bhutan: a prospective cohort study. [PDF]

Int J Emerg Med
Rinzin U, Dorjey Y, Wangchuk T, Pradhan S, Giri S, Wangdi S, Tshering U, Rinzin C.   +7 more
europepmc   +1 more source

Second report of the new Lying-in Hospital, Dublin [PDF]

Thomas Edward Beatty
openalex   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Effects of Hyperoxia and Antioxidants on Mortality, Hospital Admissions, and Myocardial Infarction After Noncardiac Surgery: 1-Year Follow-Up of a Randomized Controlled Trial. [PDF]

Acta Anaesthesiol Scand
Loft FC, Holse C, Aasvang EK, Vester-Andersen M, Rasmussen LS, Jørgensen LN, Meyhoff CS.   +6 more
europepmc   +1 more source

COURSE OF LECTURES ON THE PHYSIOLOGY AND PATHOLOGY OF THE BLOOD, AND THE OTHER ANIMAL FLUIDS, DELIVERED IN THE SESSION OF 1839-40, AT THE School of Anatomy adjoining St. George's Hospital. [PDF]

Henry Ancell
openalex   +1 more source

Age UK Rotherham Hospital Aftercare Service: Evaluation of the pilot extension into UECC and AMU at TRFT [PDF]

, 2019
Bashir, Nadia, Dayson, Christopher, Leather, David   +2 more
core  

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Correction: SGLT2 inhibitor reduces atrial tachyarrhythmia recurrence post-cryoballoon ablation: a prospective observational cohort study in patients with and without diabetes. [PDF]

BMC Cardiovasc Disord
Chen Z, Zhang L, Chen F, Han Z, Xu W.
europepmc   +1 more source

Hormone and Enzyme Mechanisms in Sebaceous Gland Excretion11From the Department of Surgery, Washington University of Medicine, and the United States Veterans Administration Hospital, St. Louis, Missouri.

, 1959
Falls B. Hershey
openalex   +1 more source