Results 151 to 160 of about 568,795 (313)

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

Dementia care in hospitals: costs and strategies [PDF]

, 2013
This report estimates the cost of dementia care in New South Wales public hospitals using a subset of data from the Hospital Dementia Services (HDS) Project conducted by the Australian Institute of Health and Welfare in conjunction with the University

core  

Evaluation of the Frequency of Antibiotic Stewardship for the Treatment of Pneumonia in a Tertiary Hospital (Loghman Hakim Hospital) in 2021

Novelty in Biomedicine
Background: Pneumonia is one of the common infectious diseases in the community and hospital, which can cause complications and death if not treated. Correct treatment of this disease is important.
Minoosh Shabani Barzegar, Zahra Sahraei, Latif Gachkar, Masume Sardari   +3 more
doaj  

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel, Timothy P. Siejka, Cassandra Marotta, Josh J. Y. Lee, Kelly Bertram, Terence J. O'Brien, Meng Law, Lucy Vivash, Ian H. Harding   +8 more
wiley   +1 more source

Investigation of the factors that impact on outcomes of HAART in patients at Tshwabe District Hospital

, 2011
Includes abstract.Includes bibliographical references (leaves 61-67).The study was conducted at Tshwane District Hospital (TDH) in Pretoria, Gauteng Province, South Africa.
Venter, Sasje
core  

Additional file 1 of Nomogram for hospital-acquired venous thromboembolism among patients with cardiovascular diseases

Additional file 1. Supplementary methods. Table S1. ICD code of outcome events. Table S2. Number of patients with cardiovascular diseases. Table S3.
Xin Li (51274), Qin Luo (2182514), Weixian Yang (845778), Zhihui Zhao (228957), Zhihong Liu (112690), Qing Zhao (170569)   +5 more
core   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

A Hospital-Based Assessment of the Acquired Demyelinating Diseases in Children: A Retrospective Study

AbstractAim: The aim of the present study was to assess the acquired demyelinating diseases in children.Methods: The present study was conducted in the Department of Paediatrics, IGIMS, Patna, Bihar, India fromDecember 2016 to November 2018. A total of 50 patients were enrolled in the study.Results: Of these, 33 (66%) cases were of acquired ...
Raju Kumar, Jayant Prakash
openaire   +2 more sources