Results 131 to 140 of about 568,795 (313)

Point Prevalence of Hospital-Acquired Infections in Ege University Hospital

, 2015
Introduction: The prevalence of hospital-acquired or healthcare-associated infections (HAI) varies from country to country even between different units of the same hospital.
Hüseyin Aytaç ERDEM, Oğuz Reşat SİPAHİ, Ulusoy, Behiye, Demet DİKİŞ, cilli, Feriha, Şükran Akşit BARIK, Sercan ULUSOY, Korkmaz, Nilay Bilgili, Sipahi, Oguz Resat, Ulusoy, Sercan, Kucukler, Nilgun Deniz, Ozinel, Mehmet Ali, Nilay KORKMAZ, Mehmet Ali ÖZİNEL, Nurhayat KEPELİ, Arda, Bilgin, Behiye ULUSOY, Feriha ÇİLLİ, Dikis, Demet, Bilgin ARDA, Erdem, Huseyin Aytac, Nilgün Deniz KÜÇÜKLER, Kepeli, Nurhayat, Barik, Sukran Aksit   +23 more
core   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Differences in microbial etiology between hospital-acquired pneumonia and ventilator-associated pneumonia: a single-center retrospective study in Guang Zhou

, 2019
Ding-Yun Feng,1,* Yu-Qi Zhou,1,* Xiao-Ling Zou,1 Mi Zhou,2 Jia-Xin Zhu,1 Yan-Hong Wang,1 Tian-Tuo Zhang11Department of Pulmonary and Critical Care Medicine, Third Affiliated Hospital of Sun Yat-sen University, Institute of Respiratory Diseases of Sun Yat-
Zhou M, Zhang TT, Zou XL, Zhu JX, Feng DY, Wang YH, Zhou YQ   +6 more
core  

High prevalence of nasal MRSA carriage in slaughterhouse workers in contact with live pigs in The Netherlands.

, 2010
Item does not contain fulltextLivestock-associated MRSA has been found in various animals, livestock farmers and retail meat. This study aimed to determine the prevalence and determinants of nasal MRSA carriage in pig slaughterhouse workers.
Kluytmans, J.A., Voss, A., Cleef, B.A.G.L., van, Mulders, M.N., Broens, E.M., Kluijtmans, J.A.J.W., Cleef, B.A. van, van Benthem, B.H.B., van Cleef, B.A.G.L., Benthem, B.H. van, Giessen, A.W., van de, Huijsdens, X.W., Giessen, A.W. Van De, van de Giessen, A.W., Zuchner, L., Kluytmans, J.A.J.W., Benthem, B.H.B., van, Voss, A   +17 more
core   +1 more source

Hospital Acquired Sepsis, Disease Prevalence, and Recent Advances in Sepsis Mitigation

Pathogens
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection, commonly associated with nosocomial transmission. Gram-negative bacterial species are particularly problematic due to the release of the lipopolysaccharide toxins upon cell death. The lipopolysaccharide toxin of E.
openaire   +3 more sources

Risk of Noncommunicable Diseases After Hospitalization for Community-Acquired Pneumonia

Open Forum Infectious Diseases
Abstract Background Community-acquired pneumonia (CAP) is a leading cause of hospitalization and mortality. Increasing evidence suggests that CAP may contribute to long-term morbidity through the development of noncommunicable diseases (NCDs).
Julio Ramirez, Stephen Furmanek, Thomas Chandler, Rodrigo Cavallazzi, Anupama Raghuram   +4 more
openaire   +2 more sources

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Frequency of Major Transmitted Integrase Resistance in Poland Remains Low Despite Change in Subtype Variability

Viruses
With the widespread use of integrase inhibitors and the expanding use of long-acting cabotegravir in both pre-exposure prophylaxis and antiretroviral treatment, molecular surveillance on the transmission of integrase resistance has regained clinical ...
Kaja Mielczak, Karol Serwin, Anna Urbańska, Bogusz Aksak-Wąs, Malwina Karasińska-Cieślak, Elżbieta Mularska, Adam Witor, Paweł Jakubowski, Maria Hlebowicz, Monika Bociąga-Jasik, Elżbieta Jabłonowska, Aleksandra Szymczak, Bartosz Szetela, Władysław Łojewski, Miłosz Parczewski   +14 more
doaj   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source