Results 121 to 130 of about 568,795 (313)

The transmission of nosocomial pathogens in an intensive care unit: a space–time clustering and structural equation modelling approach

, 2010
We investigated the incidence of cases of nosocomial pathogens and risk factors in an intensive treatment unit ward to determine if the number of cases is dependent on location of patients and the colonization/infection history of the ward.
Sheridan, E. A., Rushton, Steven, Lanyon, Clare, O'Donnell, Anthony, Shirley, Mark   +4 more
core   +1 more source

Anxiety levels and physiological responses during top-rope and lead climbing: a cross-sectional study among sport climbers

BMC Sports Science, Medicine and Rehabilitation
Objectives Sport climbing presents an exceptionally interesting research field for issues related to anxiety and stress. This discipline, classified as an extreme sport, requires participants not only to be in very good physical condition, but also to be
Natalia Swinarska, Patrycja Krężel, Aleksandra Hapka, Anna Jurczak, Sylwia Wieder-Huszla   +4 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

A Study on Antibiotic Related Resistance in UTI Patients: A Comparison Between Community Acquired and Hospital Acquired E. Coli

National Journal of Community Medicine, 2012
Background: UTI (urinary tract infection) is the most common among all hospital acquired infections world wide. In UTI, most common organism is E.coli.
Dharmishtha G Tada , Paragi J Gandhi , Kiran N Patel   +2 more
doaj  

Legionnaires' disease as a hospital‐acquired infection

International Journal of Clinical Practice, 1996
S, Manchanda, P J, Rees
openaire   +2 more sources

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

HIV drug resistance and antiretroviral therapy programs in Henan, China

EClinicalMedicine, 2020
Zhi-Bin Liu, Qiang Li, Huijun Guo
doaj   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Risk factors for recurrent hospital-acquired Clostridium difficile infection in a Japanese university hospital

, 2015
Mayu Hikone,1 Yusuke Ainoda,1,2 Sayaka Tago,2 Takahiro Fujita,2 Yuji Hirai,2 Kaori Takeuchi,2 Kyoichi Totsuka31Department of Infectious Diseases, Tokyo Metropolitan Bokutoh General Hospital, 2Department of Infectious Diseases, Tokyo Women's Medical ...
Hikone M, Hirai Y, Takeuchi K, Ainoda Y, Fujita T, Totsuka K, Tago S   +6 more
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source