Results 91 to 100 of about 5,163,490 (241)

Iranian Healthcare System Response to Hospital and Intensive Care Bed Requirements During the COVID‐19 Pandemic: A Cross‐Sectional Study

Health Science Reports
Background and Aims The COVID‐19 pandemic posed significant challenges to healthcare systems worldwide, including Iran. This article examines the Iranian healthcare system's response to hospital and intensive care unit (ICU) bed requirements during the ...
Fazeleh Hemmati, Kasra Jafari, Majid Mirmohammadkhani   +2 more
doaj   +1 more source

Future bed needs of James Connolly Memorial Hospital: Report of the Hospital Review Group. [PDF]

, 2000
In April 1999, a hospital group at James Connolly Memorial Hospital (JCMH) was convened to discuss and study the future bed needs at the hospital. The reasons for this review were due to concerns of a) high occupancy, b) increasing emergency admissions ...
James Connolly Memorial Hospital Review Group.
core  

Single‐Dose TACE‐Like Injection of Sustained‐Release Panobinostat/IL‐12 Polymeric Microparticles is Effective in Preclinical Liver Cancer Models

Advanced Science, EarlyView.
A novel PLGA/PBAE polymer microparticle platform revolutionizes intermediate‐stage liver cancer treatment by co‐delivering panobinostat and IL‐12 via a single TACE‐like injection. This sustained‐release system overcomes tumor immunosuppression, triggers robust innate and adaptive immune responses, and establishes tertiary lymphoid structures ...
Hongzhe Yu, Ling Li, Sachin S. Surwase, Xin Ming M. Zhou, Hongtao Qian, Joel C. Sunshine, Florin M. Selaru, Jordan J. Green   +7 more
wiley   +1 more source

Hospital bed capacity and usage across secondary healthcare providers in England during the first wave of the COVID-19 pandemic: a descriptive analysis. [PDF]

BMJ Open, 2021
Mateen BA, Wilde H, Dennis JM, Duncan A, Thomas N, McGovern A, Denaxas S, Keeling M, Vollmer S.   +8 more
europepmc   +1 more source

How Many Hospital Beds?

Inquiry: The Journal of Health Care Organization, Provision, and Financing, 2002
For many years, average bed occupancy level has been the primary measure that has guided hospital bed capacity decisions at both policy and managerial levels.
Linda V. Green
doaj   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source

Organic Nanozyme‐Embedded Biotherapeutic Thermosensitive Hydrogel for Extracellular GSH Depletion and Postoperative Tumor Suppression

Advanced Science, EarlyView.
A temperature‐sensitive hydrogel loaded with cyanine nanozymes and Escherichia coli is locally injected into postoperative tumor resection beds. Upon light irradiation, synergistic PTT and PDT work with cascaded reactive oxygen species to deplete extracellular GSH, eliminate residual tumor cells, and induce robust antitumor immune responses for ...
Cong Jiang, Zifan Yang, Rong Guo, Meng Suo, Guowei Wang, Dong Chen, Lilin Su, Fuhuan Wang, Shipeng Ning, Kelong Fan, Xuan Wang   +10 more
wiley   +1 more source

A System-Level Decision-Support Framework for Integrated Operating Room and Bed Capacity Planning Under Emergency Uncertainty

Applied System Innovation
Coordinating operating room schedules with downstream inpatient bed availability remains a critical challenge for hospitals, particularly under emergency-driven uncertainty.
Beshoy Botros, Mohamed Gheith, Amr Eltawil   +2 more
doaj   +1 more source

Changes in Hospital Performance after Ownership Conversions

Inquiry: The Journal of Health Care Organization, Provision, and Financing, 2003
This paper examines the effects of ownership conversions on hospital performance between 1987 and 1998 in areas of financial performance, staffing, capacity, and unprofitable care.
Yu-Chu Shen
doaj   +1 more source

The Adipose‐Sympathetic Nerve Crosstalk: FSTL1 as an Adipocyte‐Derived Neurotrophic Factor for WAT Browning

Advanced Science, EarlyView.
As a novel adipose‐derived neurotrophic factor, Follistatin‐like 1 is endocytosed by sympathetic neurons primarily via tropomyosin‐related kinase B. This process promotes sympathetic innervation in adipose tissue and norepinephrine release, leading to white adipose tissue browning, enhanced thermogenesis, and anti‐obesity effects in mice.
Xiao‐Wei Jia, Jia‐Xin Liu, Rui‐Ping Wang, Xue‐Qin Wu, Yao Che, Mu‐Chen Wu, Hong‐Wei Shang, Xin Lu, Tao Lu, Lu‐Lu Wang, Chun‐Yan Jiang, Dong‐Liang Fang, Chun Yang, Yan Gao   +13 more
wiley   +1 more source