Results 61 to 70 of about 3,772,071 (245)

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Hospital Review photo

, 1982
Colour photo of three nurses, two in costume, during the Hospital ...
Modbury Hospital
core   +1 more source

The Poor at Birth: Infant Auxology and Mortality at Philadelphia's Almshouse Hospital, 1848-1873 [PDF]

This paper presents an analysis of birth weights and infant mortality in mid-nineteenth century Philadelphia using obstetrics records of Philadelphia's Almshouse hospital, an institution for the poor and their offspring.
Claudia D. Goldin, Robert A. Margo
core  

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Amniotic fluid microbiota and metabolism with non-syndromic congenital heart defects: a multi-omics analysis

BMC Pregnancy and Childbirth
Background and aims Recent studies have indicated possible links between the microbiota and the fetal heart, while the relevant mechanism is still unknown.
Wenli Xu, Lu Li, Hong Kang, Meixian Wang, Yanqun Liu, Guicun Wang, Ping Yu, Juan Liang, Zhen Liu   +8 more
doaj   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Association of maternal VDR and VDBP gene polymorphisms with spontaneous preterm birth risks: a nested case–control study in China

BMC Pregnancy and Childbirth
Background The impact of vitamin D on spontaneous preterm birth (SPTB) is still not well understood. This study aimed to explore the relationship between maternal vitamin D receptor (VDR) and vitamin D-binding protein (VDBP) gene polymorphisms, as well ...
Nana Li, Mengling Zhou, Lu Li, Yuting Li, Meixian Wang, Ying Deng, Yanping Wang, Jun Zhu, Shu Zhou, Ping Yu   +9 more
doaj   +1 more source

Clinical characteristics and influencing factors of adverse outcomes following clinical pregnancy after laparoscopic tubal anastomosis

Annals of Medicine
Objective To identify clinical characteristics and risk factors for adverse pregnancy outcomes after clinical pregnancy following laparoscopic tubal anastomosis (LTA).Methods Retrospective analysis of 253 patients undergoing LTA (May 2016–December 2022 ...
Yan Guo, Xiaochuan Liu, Yuanyuan Zhang, Yunmei Ke, Jia Liu, Jiahong Tan, Yun Zhu, Na Ma, Yonghan Luo, Jie Zhang   +9 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

The maternal drug exposure birth cohort (DEBC) in China

Nature Communications
Drug exposure during pregnancy lacks global fetal safety data. The maternal drug exposure birth cohort (DEBC) study, a prospective longitudinal investigation, aims to explore the correlation of maternal drug exposure during pregnancy with pregnancy ...
Lu Li, Ke Wang, Meixian Wang, Jing Tao, Xiaohong Li, Zhen Liu, Nana Li, Xiaoxia Qiu, Hongwei Wei, Yuan Lin, Yuan He, Ying Deng, Hong Kang, Yuting Li, Ping Yu, Yanping Wang, Jun Zhu, Hanmin Liu   +17 more
doaj   +1 more source