Results 51 to 60 of about 631,830 (259)

Strategies to reduce the cancer burden and improve access to effective and affordable cancer interventions in Europe

open access: yesMolecular Oncology, EarlyView.
Comprehensive cancer centre (CCCs) and CCCs of Excellence (CCCoE) integration in healthcare. Through outreach to surrounding community hospitals, CCCs enable wider access to top‐clinical cancer treatments and care, thereby facilitating the swift enrolment of patients into data‐rich clinical trials (PI‐initiated trials testing new concepts, drug ...
Anton Berns   +4 more
wiley   +1 more source

Achieving a lean wayfinding system in complex hospital environments: Design and Through-life Management [PDF]

open access: yes
Complex products, such as buildings and other infrastructure, should aim to provide value to the customer over all stages of the product life-cycle. This paper considers some of the challenges associated with maximising customer value when designing ...
Koskela, Lauri   +2 more
core  

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

open access: yesFEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi   +2 more
wiley   +1 more source

Analysis of behaviour of reinforced concrete slab [PDF]

open access: yes, 2014
Bakalářská práce se zabývá analýzou chování stávající železobetonové, lokálně podepřené, stropní desky v nemocnici včetně 2. mezního stavu. Výpočet vnitřních sil byl proveden v programu SCIA Engineer.
Kubínek, Michal
core  

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

open access: yesFEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren   +8 more
wiley   +1 more source

Overview of building information modelling in healthcare projects [PDF]

open access: yes, 2011
In this paper, we explore how BIM functionalities together with novel management concepts and methods have been utilized in thirteen hospital projects in the United States and the United Kingdom. Secondary data collection and analysis were used as the
Dave, B   +4 more
core   +1 more source

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

open access: yesFEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu   +6 more
wiley   +1 more source

Sustainability best practice in PPP: Case study of a hospital project in the UK [PDF]

open access: yes, 2013
Globally, sustainable development has been given high priority for the Government agenda in order to achieve a balance of social, economic and environmental factors.
Smith, Andrew James, Zhou, Lei
core  

Modelling of a double‐scattering proton therapy nozzle using the FLUKA Monte Carlo code and analysis of linear energy transfer in patients treated for prostate cancer

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Background The dose‐averaged linear energy transfer (LETD) in proton therapy (PT) has in pre‐clinical studies been linked to the relative biological effectiveness (RBE) of protons. Until recently, the most common PT delivery method in prostate cancer has been double‐scattered PT, with LETD only available through dedicated Monte Carlo (MC ...
Rasmus Klitgaard   +7 more
wiley   +1 more source

Space resilience and hybrid modular architecture [PDF]

open access: yes
Objectives: This research explores the potential of Hybrid Modular Architecture (HMA) to improve hospital design and enhance healthcare infrastructure resilience. By integrating prefabricated modular components with site-specific construction, HMA offers
Iftimie, Alexandru
core   +1 more source

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