Results 61 to 70 of about 709,319 (308)

« L’hôpital-paquebot » d’Henry Bernard

open access: yesIn Situ, 2017
In 1958, Robert Debré reformed the French public hospital service by creating the centres hospitaliers et universitaires-CHU (university hospital centres).
Léo Noyer Duplaix
doaj   +1 more source

Overview of building information modelling in healthcare projects [PDF]

open access: yes, 2011
In this paper, we explore how BIM functionalities together with novel management concepts and methods have been utilized in thirteen hospital projects in the United States and the United Kingdom. Secondary data collection and analysis were used as the
Dave, B   +4 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Development of a low profile laser Doppler probe for monitoring perfusion at the patient – mattress interface [PDF]

open access: yes, 1988
The clinical importance of pressure ulcers is reviewed confirming the need for continuous monitoring of skin blood perfusion at the patient – mattress interface.
A. CALZOLARI   +9 more
core   +262 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Multifaith Room for Pediatric Cancer Center of Barcelona—An Intrahospital Public Space in the City

open access: yesReligions
The internationalization of specialized healthcare emphasizes multiculturalism, requiring adaptable hospital spaces. Sant Joan de Déu (SJD), a leading pediatric hospital managed by a Christian order, has created a multifaith room for prayer and ...
Alba Arboix-Alió, Oriol Ventura Rodà
doaj   +1 more source

Predicting the Required Volume Need for Architectural Work Using Artificial Neural Networks in Hospital Buildings

open access: yesJournal of the Civil Engineering Forum, 2019
Decision-making in construction design has an important role. The need for estimation tools of planning and project management aspects needs to develop. This paper discussed the benefits of artificial neural network methodology to overcome the problem of
Aulia Yudha Prathama
doaj   +1 more source

Barnes Hospital Bulletin [PDF]

open access: yes, 1984
https://digitalcommons.wustl.edu/bjc_barnes_bulletin/1222/thumbnail ...

core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

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