Results 51 to 60 of about 198,290 (264)

Multifaith Room for Pediatric Cancer Center of Barcelona—An Intrahospital Public Space in the City

Religions
The internationalization of specialized healthcare emphasizes multiculturalism, requiring adaptable hospital spaces. Sant Joan de Déu (SJD), a leading pediatric hospital managed by a Christian order, has created a multifaith room for prayer and ...
Alba Arboix-Alió, Oriol Ventura Rodà
doaj   +1 more source

Predicting the Required Volume Need for Architectural Work Using Artificial Neural Networks in Hospital Buildings

Journal of the Civil Engineering Forum, 2019
Decision-making in construction design has an important role. The need for estimation tools of planning and project management aspects needs to develop. This paper discussed the benefits of artificial neural network methodology to overcome the problem of
Aulia Yudha Prathama
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Standards and management requirements for the construction of operating rooms in Flying Eye Hospitals

Yanke Xuebao
With the continuous advancement and innovative application of aviation medical technology, Flying Eye Hospital, as a novel and advanced model integrating aviation technology and medical services, is progressively gaining widespread recognition and ...
ZHANG Hairong, HUANG Xiaoyan, SONG Yunhe, GAN Xiaoliang   +3 more
doaj   +1 more source

An investigation of nursing staff input for the co-design of an outpatient department [PDF]

Urbanism. Arhitectura. Constructii, 2019
Sriphat hospital, Chiang Mai, Thailand, outpatient department (OPD) is under pressure as a consequence of high patient demand. The hospital administration has, therefore, approved the construction of a new building to cater for out-patients. Research has
Tanut Waroonkun
doaj  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

BEM-based multidisciplinary design supported by artificial intelligence for the creation of cognitive and sustainable smart hospitals [PDF]

E3S Web of Conferences
Healthcare facilities are characterized by a high level of construction and management complexity. Digital transformation and the green transition (Twin Transition) require integrated, multidisciplinary design based on BIM (Building Information Modeling)
Prete Daniele, Piscitelli Prisco, Elia Gianluca   +2 more
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

The Hospital Town of «the First Garden City in Russia» near Prozorovka: the History of Design and Construction (1912-1930)

Academia: Архитектура и строительство, 2018
The article is devoted to the buildings of the hospital town an implemented fragment of one of the most famous town planning projects of early 20th century.
Yulia D. Starostenko
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source