Results 101 to 110 of about 41,228 (244)

Measurement of secondary esophageal motility by Endoluminal Functional Lumen Imaging Probe (EndoFLIP) in young patients with pediatric feeding disorder with and without persistent dysphagia

open access: yes
JPGN Reports, EarlyView.
Gurleen Kaur Kahlon   +6 more
wiley   +1 more source

Micro‐ultrasonography‐ vs MRI‐targeted biopsy in prostate cancer: Updated systematic review and meta‐analysis

open access: yesBJU International, EarlyView.
Objective To refine prostate cancer (PCa) pathways by comparing micro‐ultrasonography‐targeted biopsy (micro‐US‐TBx) with magnetic resonance imaging (MRI)‐TBx for detecting clinically significant PCa (csPCa) and by evaluating diagnostic accuracy (sensitivity, specificity, positive predictive value, negative predictive value).
José Pedro Cassemiro Micheleto   +12 more
wiley   +1 more source

Fn14 signalling participates in pristane‐induced murine lupus through exacerbating oxidative stress

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by oxidative stress and immune dysregulation. Fibroblast growth factor‐inducible 14 (Fn14) has been implicated in tissue injury, but its specific role in SLE pathogenesis remains unclear.
Zhu Yan   +8 more
wiley   +1 more source

Relationship Between PTBP1 and Pancreatic Cancer Based on microRNA and Behavior During TYMS‐Mediated Carcinogenesis

open access: yesCancer Science, EarlyView.
Corresponding Author and colleagues identify a pancreas‐enriched microRNA, miR‐216b‐5p, that suppresses PTBP1 and its downstream effector TYMS. Their findings reveal a novel miR‐216b‐5p/PTBP1/TYMS regulatory axis driving pancreatic cancer progression and establish PTBP1 as a central molecular regulator of tumor biology beyond its metabolic role ...
Shigenori Suzuki   +14 more
wiley   +1 more source

USP34 Haploinsufficiency as a Cause of Neurodevelopmental Phenotypes

open access: yesClinical Genetics, EarlyView.
Heterozygous loss‐of‐function variants in USP34 cause a novel neurodevelopmental disorder characterized by global developmental delay, speech impairment, autism, hypotonia, craniofacial dysmorphism, and distal limb anomalies. Disrupted Wnt/β‐catenin signaling via reduced Axin stabilization refines gene‐specific contributions within 2p15p16.1 ...
Helena Wigoda   +10 more
wiley   +1 more source

Patch Test Results With Additions to the European Baseline Series, 2021/22—Joint European Results of the ESSCAA and the EBSB Working Groups of the ESCD, and the GEIDACC

open access: yesContact Dermatitis, EarlyView.
ABSTRACT Background Allergens are periodically added to the European Baseline Series (EBS) to audit their value in consecutive patch testing. Objectives To present results of audit allergens tested in consecutive patients in 54 departments in 13 European countries during 2021 and 2022.
Wolfgang Uter   +68 more
wiley   +1 more source

ITGA5 as a Dual Regulator of Epithelial‐Mesenchymal Transition and Epithelial Cell Anoikis Resistance: Functional Validation and Drug Prediction

open access: yesCell Proliferation, EarlyView.
Proteomics and functional validation reveal ITGA5 as a dual promoter of epithelial‐mesenchymal transition and anoikis resistance in human bronchial epithelium: targeting ITGA5 represents a novel therapeutic strategy for asthma airway remodelling. ABSTRACT Airway remodelling is a major contributor to persistent airflow limitation and irreversible lung ...
Ting Wang   +10 more
wiley   +1 more source

Crisis epilépticas en niños con síndrome de Dravet en condiciones de calor extremo: estudio cualitativo de la perspectiva de los progenitores

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Resumen Objetivo Describir la experiencia de progenitores de niños y adolescentes con síndrome de Dravet en relación con el impacto de las olas de calor o las altas temperaturas ambientales en las crisis epilépticas de sus hijos, así como las estrategias de afrontamiento empleadas.
Angel Aledo‐Serrano   +8 more
wiley   +1 more source

Inclusão de usuários de hospital-dia em saúde mental: uma revisão

open access: yes, 2014
Revisar os estudos sobre hospital-dia em saúde mental no Brasil para conhecer as estratégias terapêuticas de inclusão social de seus usuários, as medidas de apoio e o grau de satisfação da família com o serviço de saúde mental. Revisão realizada em bases de dados eletrônicas (Lilacs e SciELO), em artigos nacionais publicados entre janeiro de 2001 e ...
Weber,César Augusto Trinta   +1 more
openaire   +1 more source

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