Results 121 to 130 of about 489,914 (273)
Relationship Between PTBP1 and Pancreatic Cancer Based on microRNA and Behavior During TYMS‐Mediated Carcinogenesis
Cancer Science, EarlyView.Corresponding Author and colleagues identify a pancreas‐enriched microRNA, miR‐216b‐5p, that suppresses PTBP1 and its downstream effector TYMS. Their findings reveal a novel miR‐216b‐5p/PTBP1/TYMS regulatory axis driving pancreatic cancer progression and establish PTBP1 as a central molecular regulator of tumor biology beyond its metabolic role ...Shigenori Suzuki, Hiroaki Hase, Yosuke Inomata, Jun Arima, Kentaro Jingushi, Atsushi Tomioka, Nao Kawaguchi, Hiroki Hamamoto, Ryo Tanaka, Yoshiro Imai, Mitsuhiro Asakuma, Tomohito Tanaka, Kazutake Tsujikawa, Kohei Taniguchi, Sang‐Woong Lee +14 morewiley +1 more sourceInclusão de usuários de hospital-dia em saúde mental: uma revisão
, 2014 Revisar os estudos sobre hospital-dia em saúde mental no Brasil para conhecer as estratégias terapêuticas de inclusão social de seus usuários, as medidas de apoio e o grau de satisfação da família com o serviço de saúde mental. Revisão realizada em bases de dados eletrônicas (Lilacs e SciELO), em artigos nacionais publicados entre janeiro de 2001 e ...Weber, César Augusto Trinta, Juruena, Mário Francisco +1 moreopenaire +1 more sourcePatch Test Results With the European Baseline Series, 2021/2022—Joint European Results of the ESSCAA and the EBSB Working Groups of the ESCD, and the GEIDACC
Contact Dermatitis, EarlyView.ABSTRACT Background
Patch test results obtained with the European Baseline Series (EBS) in its current version serve both contact allergy surveillance and (re‐)assessing the diagnostic value of EBS allergens. Objectives
To present results of current EBS patch testing, obtained in 59 departments in 14 European countries during 2021 and 2022.Wolfgang Uter, S. Mark Wilkinson, Olivier Aerts, Andrea Bauer, Leopoldo Borrego, Richard Brans, Timo Buhl, Heinrich Dickel, Aleksandra Dugonik, Francesca Larese Filon, Ana Giménez Arnau, Cataldo Patruno, Györgyi Pónyai, Stamatis Gregoriou, Steffen Schubert, Dagmar Simon, Luca Stingeni, Skaidra Valiukevičienė, Elke Weisshaar, Thomas Werfel, Margarida Gonçalo, Marie‐L. A. Schuttelaar, ESSCAA and EBSB ESCD Working Groups, and the GEIDACC, Birger Kränke, Alexander Navarini, Philip Spring, Ulrike Beiteke, Cecilia Dietrich, Sibylle Schliemann, Detlef Becker, Swen Malte John, Nicola Wagner, Dimitra Koumaki, Maddalena Napolitano, Anna Belloni Fortina, Francesca Larese Filon, Rosella Gallo, Thomas Rustemeyer, Radoslaw Spiewak, Maja Kalac Pandurovic, Tanja Kmecl, Mojca Simončič Godnič, Nada Kecelj, Philippa Cousen, Ella Dendooven, Juan Francisco Silvestre Salvador, José Manuel Carrascosa Carrillo, Mónica Munera Campos, Esther Serra Baldrich, Gemma Melé‐Ninot, Cristina Barrabés Torrella, David Pesqué, María Antonia Pastor Nieto, Francisco Navarro Triviño, Inmaculada Ruiz Gonzales, Enrique Gómez de la Fuente, Susana Córdoba Guijarro, Francisco Javier Ortiz de Frutos, Fátima Tous Romero, Tatiana Sanz Sánchez, Pablo Chicharro Manso, Marta Andreu Barasoain, Marta Elosua González, Araceli Sánchez Gilo, Paloma Sánchez‐Pedreño Guillén, Pedro Mercader‐García, Carmen Paredes Suárez, María Elena Gatica Ortega, José Juan Pereyra Rodríguez, Javier Miquel Miquel, Mercedes Rodríguez Serna, Violeta Zaragoza Ninet, Ricardo González Pérez +73 morewiley +1 more sourceITGA5 as a Dual Regulator of Epithelial‐Mesenchymal Transition and Epithelial Cell Anoikis Resistance: Functional Validation and Drug Prediction
Cell Proliferation, EarlyView.Proteomics and functional validation reveal ITGA5 as a dual promoter of epithelial‐mesenchymal transition and anoikis resistance in human bronchial epithelium: targeting ITGA5 represents a novel therapeutic strategy for asthma airway remodelling. ABSTRACT
Airway remodelling is a major contributor to persistent airflow limitation and irreversible lung ...Ting Wang, Ling Rao, Xiaofang Li, Miaofen Zhang, Huiting Huang, Zhiyan Luo, Gang Liao, Yong Jiang, Shaofeng Zhan, Qiong Liu, Xiufang Huang +10 morewiley +1 more sourceEpidemiologia da paralisia cerebral no Brasil pela perspectiva da Classificação Internacional de Funcionalidade, Incapacidade e Saúde
Developmental Medicine &Child Neurology, EarlyView.Resumo Objetivo
Estabelecer uma descrição geral das pessoas com paralisia cerebral (PC) no Brasil, incluindo a epidemiologia, características clínicas, funcionalidade e acesso à reabilitação e equipamentos, pela perspectiva da Classificação Internacional de Funcionalidade, Incapacidade e Saúde (CIF), utilizando dados preliminares do Registro Brasileiro Hércules Ribeiro Leite, Luana Cristina da Silva, Elton Duarte Dantas Magalhães, Israt Jahan, Nadia Badawi, Gulam Khandaker, Maysa Ferreira Martins Ribeiro, Juliana de Alcântara Moreira Pereira, Luma Sthephanine Viana Roque da Silva, Maria de las Mercedes Ruiz Brunner, Paula Silva de Carvalho Chagas +10 morewiley +1 more sourceAssociation between insulin resistance, lean mass and muscle torque/force in proximal versus distal body parts in healthy young men [PDF]
, 2014 Objectives:The purpose of this study was to investigate whether there is already an association of insulin resistance (IR) with muscle mass and –force/torque in an adult population and whether this relationship is the same in distal and proximal body ...Calders, Patrick, Cambier, Dirk, Goemaere, Stefan, Gysel, Tineke, Kaufman, Jean, Roman de Mettelinge, Tine, Taes, Youri, Zmierczak, Hans-Georg +7 morecore +1 more sourceExploring the psychosocial implications of general population screening for paediatric type 1 diabetes in Europe: Protocol for a mixed‐methods study
Diabetic Medicine, EarlyView.Abstract Aims
Research and policy initiatives for type 1 diabetes (T1D) across European countries demonstrate an emergent, critical shift towards universal paediatric screening. National adaptations of screening, however, remain under‐researched. The current study, as part of the EU‐funded EDENT1FI programme, aimed to examine the psychosocial impact ...O. Boiko, K. Barnard‐Kelly, J. Vercauteren, S. M. Greenfield, R. P. Dias, L. M. Quinn, I. Litchfield, T. Papanikolaou, J. L. Dunne, G. Perego, F. Gatti, F. Milano, B. M. Milazzo, V. Di Mattei, K. Lange, C. Mathieu, L. Overbergh, A.‐G. Ziegler, C. Hurtado Del Pozo, M. G. Scarale, A. Mahieu, A. J. Omar Alsaleh, E. Bosi, P. Narendran, on behalf of the EDENT1FI Consortium, C. Mathieu, P. Gillard, K. Casteels, B. van der Schueren, L. Overbergh, J. Vercauteren, A. G. Ziegler, P. Achenbach, F. Haupt, C. Winkler, S. Hummel, F. Reschke, O. Kordonouri, T. von dem Berge, K. Lange, T. Pieber, J. Mader, S. Moitzi, S. Del Prato, B. Torbeyns, Z. Sumnik, O. Cinek, V. Neuman, B. Berka, F. Pociot, B. Petersen, J. Antvorskov, J. H. Klaebel, R. Lahesmaa, H. Hyöty, J. E. Laiho, F. Reschke, O. Kordonouri, T. von dem Berge, E. Bonifacio, R. Berner, A. Hommel, A. Loff, G. Gemulla, N. Zubizarreta, E. Bosi, L. Piemonti, V. Lampasona, F. Dotta, G. Sebastiani, A. Szypowska, K. Karczewski, P. Jarosz‐Chobot, J. F. Raposo, R. Ribeiro, R. Coelho, M. Peakman, E. Niemoeller, M. Baccara‐Dinet, J. Van Rampelbergh, R. Bergholdt, K. Fogh, O. Cohen, M. I. Buompensiere, C. Hurtado del Pozo, E. Latres, G. Agiostratidou, A. Koralova, J. Jackson, D. Darrock, H. Tewson, S. Nagallas, J. Hedrick, K. Collins, T. Tree, C. Dayan, K. Hood, J. Townson, R. Playle, R. Besser, P. Narendran, I. Litchfield, S. Greenfield, R. Dias +103 morewiley +1 more sourceInsufficient control of blood pressure and incident diabetes [PDF]
, 2009 OBJECTIVE:
Incidence of type 2 diabetes might be associated with preexisting hypertension. There is no information on whether incident diabetes is predicted by blood pressure control.CHINALI, MARCELLO, DE LUCA, NICOLA, DE SIMONE, GIOVANNI, Giudice R, IACCARINO, GUIDO, IZZO, RAFFAELE, ROZZA, FRANCESCO, TRIMARCO, BRUNO, TRIMARCO, VALENTINA +8 morecore
