Results 91 to 100 of about 46,997 (260)
# Background Medical supply donation programs are crucial for addressing resource gaps in low-income settings, but their effectiveness depends on alignment with recipient needs, infrastructure, and operational capacities.
Emmanuel Tito +8 more
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Flexible surgical robots are advancing minimally invasive interventions for cardiovascular diseases and cancer by enabling precise navigation through complex, submillimeter anatomical pathways. This review highlights recent innovations in actuation, bio‐integrated sensing, AI‐assisted control, and friction‐reduction technologies, discusses current ...
Hermione Truong +14 more
wiley +1 more source
Background Safe anesthesia is fundamental to safe surgery and depends on facility readiness, team behaviors, and consistent adherence to safety standards such as the World Health Organization (WHO) Surgical Safety Checklist.
Wael Sadaqa +17 more
doaj +1 more source
Introduction Climate degradation poses a significant global health challenge, with healthcare systems paradoxically contributing to this issue while adhering to the principle of ‘do no harm’.
Nathalie Clavel +6 more
openaire +3 more sources
This study identified Danofloxacin as a novel supporter of the maintenance of mouse embryonic stem cell (ESC) pluripotency. It functions partially by inhibiting HDAC1, which increases specific histone acetylation marks and activates key genes like Tert and Prdm10.
Yan Zhang +8 more
wiley +1 more source
Deep Contrastive Learning for High‐Throughput Prediction of Drug Resistance Mutations from Sequences
This study presents DeepMutDTA, a deep learning framework aimed at predicting mutation‐induced changes in protein‐drug interactions and prioritizing variants potentially linked to drug resistance. Trained on large‐scale data, it incorporates SimSiam‐MuTF, a label‐aware contrastive fine‐tuning strategy that encourages separation between WT and MT ...
Xiaowen Hu +7 more
wiley +1 more source
Mr BMT Achieves Systemic Macrophage Replacement With Preservation of Tissue Homeostasis
Microglia replacement by bone marrow transplantation (Mr BMT) enables systemic replacement of tissue‐resident macrophages. Despite persistent macrophage and tissue remodeling across multiple organs, core biological functions and innate immune responses remain preserved, supporting long‐term maintenance of organismal homeostasis and the therapeutic ...
Yufei Xu +17 more
wiley +1 more source
Kevin R Mitchell,1– 3 Alison Bomm,3,4 Barry S Shea,2,3,5 Douglas Shemin,1– 3 George Bayliss1– 3 1Division of Kidney Diseases and Hypertension, Brown Medicine, Providence, RI, USA; 2Alpert Medical School, Brown University, Providence, RI,
Mitchell KR +4 more
doaj
A Critical Time Window of Neocortex Modulation for Remote Fear Memory in Rats and Humans
This study identifies a delayed consolidation window around 18 h after fear learning in the mPFC essential for remote fear memory. VTA dopaminergic input during this window sustains remote memory in rats, while non‐invasive stimulation of homologous human mPFC at the corresponding time selectively weakens remote but not recent fear memory, revealing a ...
Lu Cao +19 more
wiley +1 more source
Background: Supply chain management process allows the right laboratory commodities in the right quantities in the right condition delivered to the right place at the right time for the right cost. Poor management of laboratory equipment, reagents and other suppliers with recurrent stock-outs of reagents, frequent equipment breakdown was a major gap in
openaire +1 more source

