Results 81 to 90 of about 44,349 (245)

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

Advanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang, Wing Yan Chung, Serena M. Pulente, Yubin Lei, Khang Nguyen, Eddie Tam, Nadya M. Morrow, Ilka Lorenzen‐Schmidt, Fengxia Xiao, Augusto Zani, Dylan Burger, Hye Kyoung Sung, Erin E. Mulvihill, Gary Sweeney   +13 more
wiley   +1 more source

Enhanced Endoscopic Internal Drainage of Gastric Abscess Through Additively Manufactured Stents

Advanced Healthcare Materials, EarlyView.
Postoperative gastric leaks are often treated with off‐label biliary double‐pigtail stents, yet conventional extruded designs are not optimized for leak anatomy, can migrate, and may limit abscess evacuation. PETALS is introduced to optimize transmural drainage geometry and enable patient‐specific 3D‐printable stents.
Parima Phowarasoontorn, Yongbin Ko, Juan S. Barajas‐Gamboa, Juan P. Pantoja, Oraib Al‐Ketan, Mohamed Ali, Sungyun Sohn, Heba Tageldeen Naser, Abdel‐Hameed Dabbour, Batoul Khlaifat, Ahmed AlZubaidi, Carlos Abril Vega, John Rodriguez, Matthew Kroh, Khalil B. Ramadi   +14 more
wiley   +1 more source

Understanding healthcare providers' perspectives on barriers to accessing stroke care at a resource-limited hospital in East Africa: A qualitative study from Mnazi Mmoja Referral Hospital in Zanzibar.

PLOS Global Public Health
Timely and appropriate care reduces the risk of mortality and disability after stroke. Despite high stroke incidence, little is known about the specific barriers to accessing stroke care in Zanzibar, East Africa.
Jutta M Adelin Jørgensen, Elias Ditlevsen, Sanaa S Said, Richard W Walker, Dirk Lund Christensen, Karoline Kragelund Nielsen   +5 more
doaj   +1 more source

Oxygen Supply of Islets of Langerhans by Photosynthetically Active Microalgae in Bioprinted Co‐Cultures Maintains Their Function in a Hypoxic Environment

Advanced Healthcare Materials, EarlyView.
This study developed a bioprinted co‐culture system embedding rat pancreatic islets and Scenedesmus sp. microalgae spatially defined in close vicinity. Red light was found optimal to ensure microalgal photosynthesis while maintaining islet viability and functionality. A tailored co‐culture medium supported both cell types.
Finn Dani, Sarah Duin, Ashwini Rahul Akkineni, Susann Lehmann, Barbara Ludwig, Michael Kühl, Michael Gelinsky, Anja Lode   +7 more
wiley   +1 more source

Laboratory diagnostics performance in Uganda: A survey of test availability and constraints

Journal of Interventional Epidemiology and Public Health
Introduction: Clinical laboratory services are a critical component of the health system for effective disease diagnosis, treatment, control and prevention. However, many laboratories in Sub-Saharan Africa remain dysfunctional.
Noel Namuhani, Suzanne Namusoke Kiwanuka, Martha Akulume, Simeon Kalyesubula, William Bazeyo, Angela Nakanwagi Kisakye   +5 more
doaj   +1 more source

Elastomeric Micro‐Balloons for Remote Control of Cerebral Blood Flow and Real‐Time In vivo Imaging of Rodent Brain Response to Hypoperfusion

Advanced Materials, EarlyView.
This study reports the fabrication of MRI‐compatible elastomeric micro‐balloons via a multi‐step bubble casting process, where the monolithic elastomeric wall is selectively stiffened for reversible and controlled inflation and elasticity, depending on the target vessels for graded occlusion of cerebral arteries.
Jong Bin Kim, Jinghui Wang, Yinding Chi, Jingxian Wu, Alicia Ng, Guanda Qiao, Honglin Tan, Miroslaw Janowski, Piotr Walczak, Yajie Liang, Shu Yang   +10 more
wiley   +1 more source

Hydrogel‐Based Airway‐on‐Tube With Perfusable Endothelial Lumen and Outward Epithelialization

Advanced Materials, EarlyView.
A hydrogel‐based airway‐on‐tube platform featuring a perfusable endothelial lumen and outward epithelialization is presented. The system supports primary human bronchial epithelial and lung microvascular endothelial coculture under air‐liquid interface conditions.
Ali Doryab, Jack F. Murphy, Michael Bartolf‐Kopp, Jenny C‐C Hsin, Alice Chernaik, Frank McCaughan, Yan Yan Shery Huang, Tomasz Jungst, Jürgen Groll   +8 more
wiley   +1 more source

Impact of medical supply donations: a post-donation survey in a critical access hospital in Douala, Cameroon

Journal of Global Health Economics and Policy
# Background Medical supply donation programs are crucial for addressing resource gaps in low-income settings, but their effectiveness depends on alignment with recipient needs, infrastructure, and operational capacities.
Emmanuel Tito, Etienne Ngeh Ngeh, Ines Kafando, Fatima Halilu, Ope Olayinka, Saanvi Dixit, Oriane Taku, Anita Tito, Peter Ebasone   +8 more
doaj   +1 more source

3D Printed Multimaterial Microfluidic Transistors

Advanced Materials Technologies, EarlyView.
We introduce a biocompatible, high resolution photopolymer resin that closely mimics the Young's Modulus (elasticity) and reversible stretchability (no hysteresis) of poly(dimethylsiloxane) (PDMS), enabling the fabrication of microfluidic transistors (i.e., microvalves capable of proportional amplification) by multimaterial stereolithography (mSLA ...
Alireza Ahmadianyazdi, Wei Huang, Kaustav A. Gopinathan, Ivan Stepanov, Lisa Horowitz, Ting‐Yuan Tu, Mehmet Toner, Albert Folch   +7 more
wiley   +1 more source

Identified practice gaps and opportunities in anesthesia safety across 14 Arab countries: a multicenter study

Patient Safety in Surgery
Background Safe anesthesia is fundamental to safe surgery and depends on facility readiness, team behaviors, and consistent adherence to safety standards such as the World Health Organization (WHO) Surgical Safety Checklist.
Wael Sadaqa, Ahmad Abdulrahman Daqqa, Anas Hamdan, Ali Shawqi Saadoon, Abdelhaq Elmansori, Mehdi Trifa, Hesham Albabtain, Gunida Alguneid, Asim Osman, Maroun Ghabach, Abdullah Al-Naggar, Randah A. Zaineldin, Ahmed Shahin, Abdulsatar Ravalia, Mohammad Safi, Khalil Abuarqub, Malik Alqub, Mohammad Masu’d   +17 more
doaj   +1 more source