Results 91 to 100 of about 4,138,785 (243)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Ranking of University Hospitals in Yazd based on National Nursing Indicators by AHP-TOPSIS Technique in 2016

open access: yesJournal of Community Health Research, 2016
Introduction: Hospitals as one of the main organizations of rendering services and the most costly operational units of the health system are of special importance.
Mohammad Sadeghi   +2 more
doaj  

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

The Relationship of Quality Improvement and Patient Safety with Performance Indicators in Shahid Beheshti University of Medical Science Teaching Hospitals

open access: yesپیاورد سلامت, 2016
Background and Aim: In health sector, improving quality of treatment services and patient safety are considered as vital. The objective of this study was to determine the relationship between the quality improvement and patient safety (QPS) and the ...
Amir Ashkan Nasiripour, Shirin Jafari
doaj  

Rational Drug-Use Evaluation Based on World Health Organization Core Drug-Use Indicators in a Tertiary Referral Hospital, Northeast Ethiopia: A Cross-Sectional Study

open access: yesDrug, Healthcare and Patient Safety, 2020
Desalegn Birara Mamo, 1 Belete Kassa Alemu 2 1Medicine Department, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia; 2Department of Pharmacy, Pharmacology and Toxicology Unit, College of Medicine and Health Sciences, Wollo ...
Mamo DB, Alemu BK
doaj  

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Hospital Ward photo

open access: yes
Black and white photo of some beds in an empty ward in Modbury ...
Modbury Hospital
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

The Potential of Medical Tourist\'s attraction in Hospitals (A Case Study of a Military Hospitals in Tehran)

open access: yesبیمارستان, 2016
Background: Many hospitals of Iran make use of their therapeutic capacities in order to attract medical tourists and increase revenue and efficiency of their affiliated hospitals. This issue has major benefits for hospital and tourists.
Sayed Masood Mosavi-negad   +4 more
doaj  

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