Results 101 to 110 of about 5,317,428 (385)

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Presenting an Integrated Architecture of Hospital Information Systems Based on Interoperability Model: Clinical Information Systems

مجله انفورماتیک سلامت و زیست پزشکی, 2022
Introduction: Hospital information system (HIS) as an integrated information system is used for daily operations, planning, care, and treatment of patients.
Fatemeh Moshiri, Abbas Asosheh
doaj  

Internações no sistema de serviços hospitalares, SUS e não SUS: Brasil, 2006 Hospital admissions in the hospital health care system, SUS and non-SUS: Brazil, 2006

Revista Brasileira de Epidemiologia, 2011
O objetivo deste estudo foi descrever as admissões, SUS e não SUS, no Sistema de Serviços Hospitalares no Brasil no ano de 2006, adotando o indivíduo internado como unidade de análise. As fontes dos dados foram o Sistema de Informação Hospitalar (SIH/SUS)
Marizélia Leão Moreira, Hillegonda Maria DutilhNovaes   +1 more
doaj   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren, Moana Busch, Pedro A. Ruiz, Ermanno Malagola, Valeria Baumeler, Federica Foti, Adelina Gross, Tobias Grütter, Hendrik Edel, Cordelia Schuler, Kristina Handler, Glenn De Lange, Isabelle C. Arnold, Cheryl de Vallière, Klaus Seuwen, Martin Hausmann, Gerhard Rogler   +16 more
wiley   +1 more source

Determinantes da morbidade hospitalar em região do Estado de São Paulo (Brasil)

Revista de Saúde Pública
INTRODUÇÃO: Muitas mudanças ocorreram no perfil da morbidade dos pacientes atendidos nos hospitais do País nos últimos anos, seja em função de fatores demográficos, epidemiológicos, financeiros, tecnológicos ou da estrutura dos serviços.
Maria Lúcia Lebrão
doaj  

Rare Diseases in Hospital Information Systems-An Interoperable Methodology for Distributed Data Quality Assessments. [PDF]

Methods Inf Med, 2023
Tahar K, Martin T, Mou Y, Verbuecheln R, Graessner H, Krefting D.   +5 more
europepmc   +1 more source

Hospital Information Systems: A Review in Perspective [PDF]

Yearbook of Medical Informatics, 1994
AbstractThe demand for information for health care is increasing exponentially in volume, content and the number and geographical distribution of users. Most HIS systems commercially available today are based on designs and philosophies of the 1970s. Even though new technology has improved these systems’ performance, to meet current demands, concepts ...
openaire   +2 more sources

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Explanatory factors for the variation in hospitalizations Factores que explican la variación en el número de hospitalizaciones Fatores explicativos para a variação na produção de internações hospitalares

Revista Latino-Americana de Enfermagem, 2008
In the implementation/consolidation process of the Brazilian Single Health System (SUS), hospitalization deserves special attention from the local management. This descriptive study identifies, through qualitative data, factors that explain variations in
Lucieli Dias Pedreschi Chaves, Maria Luiza Anselmi   +1 more
doaj   +1 more source

Current landscape of hospital information systems in gynecology and obstetrics in Germany: a survey of the commission Digital Medicine of the German Society for Gynecology and Obstetrics. [PDF]

Arch Gynecol Obstet, 2023
Pfob A, Griewing S, Seitz K, Hillen C, Becker S, Bayer C, Wagner U, Fasching P, Wallwiener M, Kommission Digitale Medizin, Deutsche Gesellschaft für Gynäkologie und Gebursthilfe (DGGG).   +10 more
europepmc   +1 more source