Results 141 to 150 of about 5,317,428 (385)

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

The Relationship between Quality of Service Providing Software Systems and User Satisfaction in Selected Hospitals of Tehran University of Medical Sciences

open access: yesبیمارستان, 2016
Background: Medical centers and hospitals need to expand internet, Application Service Providing (ASP) to convert it to a long-lasting choice to compete. Hence, the present study carried out with the aim of determining the relationship between quality of
Zahra Maebood Mojdehi   +2 more
doaj  

Endoglin mediates the tumor‐ and metastasis‐promoting traits of stromal myofibroblasts in human breast carcinomas

open access: yesMolecular Oncology, EarlyView.
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo   +11 more
wiley   +1 more source

Business Process Redesign in the Perioperative Process: A Case Perspective for Digital Transformation [PDF]

open access: yes, 2019
This case study investigates business process redesign within the perioperative process as a method to achieve digital transformation. Specific perioperative sub-processes are targeted for re-design and digitalization, which yield improvement. Based on a
Daily, Sandra   +3 more
core   +1 more source

Determining Indicators for Evaluating Hospital Information System Architecture

open access: yesمدیریت اطلاعات سلامت, 2015
Introduction: Although the current architecture of information systems as necessary step in the process of establishing hospital information systems have been considered.Continuous evaluation of hospital information systems to determine the extent ...
Sedigheh Erfani   +2 more
doaj  

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

open access: yesMolecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková   +14 more
wiley   +1 more source

Ipteks Faktor – Faktor Penghambat Proses Pelaporan Data Sistem Informasi Rumah Sakit (Sirs) Berbasis Online pada Rsup Prof. Dr. R. D. Kandou Manado [PDF]

open access: yes, 2018
According to Permenkes Republic of Indonesia Number 1171 / MENKES / PER / VI / 2011 concerning SIRS that every hospital is required to implement an online hospital information system to improve the quality of services to hospitals. But in this case there
Kalalo, M. Y. (Meily)   +1 more
core  

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

Implementasi Sistem Informasi Administrasi Rumah Sakit Berbasis Kumputer Untuk Meningkatkan Kinerja Karyawan (Studi Pada Billing Systems RSUD Dr.saiful Anwar Malang) [PDF]

open access: yes, 2013
General hospital Dr. Saiful Anwar Malang is a general hospital “A” class that has been fully accredited and certified ISO 9001: 2008. As public hospitals of the area would to have a good administrative information system in order to serve visitors to the
Khairani, T. (Tiara)
core  

Usability Evaluation of Hospital Information Systems Based on Isometric Standard from the Viewpoint of Usersin Education and Treatment Centers Affiliated to Qom University of Medical Sciences, Iran

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2014
Background and Objectives: Evaluation has an important role in software development. Quality is considered in the evaluation of information systems, which depends on usability, availability, validity, compatibility, and response time.
Atefeh Mousavi   +3 more
doaj  

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