Results 31 to 40 of about 460,810 (250)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Research status and development trend of extracorporeal membrane oxygenation based on bibliometrics
Frontiers in Cardiovascular Medicine, 2023 BackgroundUsing bibliometric method to analyze the research status and development trend of extracorporeal membrane oxygenation (ECMO), we aim to provide clinicians, scientists, and stakeholders with the most up-to-date and comprehensive overview of ECMO
Cuizhong Guan +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
GMS Medizin – Bibliothek – Information, 2011 The recent issue 1-2/2011 of GMS Medizin – Bibliothek – Information has a focus on hospital libraries, pharmaceutical libraries and veterinary medical libraries.
Bauer, Bruno
doaj
Volunteers@your library: benefits and pitfalls of volunteers in hospital libraries
Journal of the Canadian Health Libraries Association, 2004 The purpose of this survey was to explore the attitudes of hospital library managers toward the use of library volunteers. During April 2003 a questionnaire was mailed to 89 Ontario hospital library managers.
Mary McDiarmid, Ethel W Auster
doaj +1 more source
The Library as a Hospitable Place: Hospitality and Welcoming Volunteers
The Library QuarterlyLibraries use volunteers. Research indicates various barriers to volunteering. After these barriers have been overcome, it is of great importance that the volunteer is welcomed into the organization. Therefore, hospitality is not just about receiving patrons but also receiving (new) volunteers.
Duursma, Geesje +2 more
openaire +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source