Results 41 to 50 of about 15,897,913 (288)

Silmitasertib-induced macropinocytosis promoting DDP intracellular uptake to enhance cell apoptosis in oral squamous cell carcinoma

open access: yesDrug Delivery, 2021
Cisplatin (DDP) is a first-line chemotherapeutic drug applied for the treatment of oral squamous cell carcinoma (OSCC). The anticancer activity of DDP is tightly linked to its intracellular uptake.
Shaojuan Song   +7 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

The Use of RFID in Hospital Systems: An Analysis of International Journals

open access: yesGEPROS: Gestão da Produção, Operações e Sistemas, 2019
The flow of people, materials and equipment in hospitals is high, making its management a complex task, since care must be taken to ensure the life and safety of patients.
Isabela Maria Monteiro Vieira   +4 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Evaluation and Prioritization of Hospital Management Roles from Experts\' Point of View (Study Case: Imam Khomeini Hospital (RA)) [PDF]

open access: yesبیمارستان, 2023
Background: Achieving goals and developing hospital services depends on competence and optimal management. There will be competent managers who can be successful in performing managerial roles.
Rohollh Hosseini, Anis Javanmard
doaj  

A Brief History of Katherine Hospital 1934-1994

open access: yes, 1994
Compiled by Jo Ascott on behalf of The Katherine Hospital Management Board to commemorate the 60th Anniversary of the establishment of Katherine Hospital.
Ascott, Jo   +1 more
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Hospital wastes management in Mazandaran Province with emphasis on genotoxic waste management

open access: yesسلامت و محیط, 2019
Background and Objective: Hospital wastes with the content of infectious, pathologic, sharp, pharmaceupitical and genotoxic materials are classified as hazardous wastes.
J Gorgani   +7 more
doaj  

Chairman's report / East Arm Hospital Management Board.

open access: yes, 1982
Aided by the experiences of the 1980-1981 period, the East Arm Hospital Management Board looked forward to its role for the next period. Between July 1981 to 31 March 1982 the Board made a significant contribution for the overall good of the hospital and

core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

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