Results 61 to 70 of about 15,897,913 (288)
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Black and white photos of the developments of Modbury Hospital in August ...
Modbury Hospital
core +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Colour photo of three nurses, two in costume, during the Hospital ...
Modbury Hospital
core +1 more source
PENILAIAN BAHAN BERBAHAYA BERACUN PADA LABORATORIUM RADIOLOGI RSUD BANGIL KABUPATEN PASURUAN
The consequence of activity in hospital is to produce toxic material waste (B3). So, description of B3 in the hospital was needed. The objective of this research was to identify the hazards in each stage in waste management of Liquid Hazardous and Toxic (
Frans Salesman, Umi Farida
doaj +1 more source
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
Planning for Hospital Pharmacy Management, Now and in the Future [PDF]
Where have all the pharmacy managers gone? This question has garnered the attention of hospital pharmacists across Canada in the wake of changing management roles, the appointment of nonpharmacist managers, and ongoing vacancies in formal leadership ...
Management Task Force, CSHP Hospital Pharmacy
core +1 more source
Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source
Industrialisation and service provision expose involved people to occupational health risks, including solid waste workers. In Zimbabwe, many concerns focus on occupational health risks affecting workers in industries, giving little attention to those ...
Steven Jerie +4 more
doaj +1 more source

