Development of a nomogram for predicting in-hospital mortality of patients with exacerbation of chronic obstructive pulmonary disease [PDF]
, 2017 Yukiyo Sakamoto,1 Yasuhiro Yamauchi,1 Hideo Yasunaga,2 Hideyuki Takeshima,1 Wakae Hasegawa,1 Taisuke Jo,1,3 Yusuke Sasabuchi,3 Hiroki Matsui,2 Kiyohide Fushimi,4 Takahide Nagase1 1Department of Respiratory Medicine, Graduate School of Medicine ...
Sakamoto Y +9 more
core
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
The Poor at Birth: Infant Auxology and Mortality at Philadelphia's Almshouse Hospital, 1848-1873 [PDF]
This paper presents an analysis of birth weights and infant mortality in mid-nineteenth century Philadelphia using obstetrics records of Philadelphia's Almshouse hospital, an institution for the poor and their offspring.
Claudia D. Goldin, Robert A. Margo
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Restructuring and hospital care: Sub-national trends, differentials, and their impacts; New Zealand from 1981 [PDF]
, 2009 An analysis of the "nation's health" is the central concern of this study. Its genesis was a detailed, technical, time-series research on regional and ethnic differentials in health in New Zealand.
Jackson, Gary +8 more
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Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
Does disability explain state-level differences in the quality of Medicare beneficiary hospital inpatient care? [PDF]
Almost 20 percent of the total U.S. population and 42 percent of the population over the age of sixty-six are disabled. Research has shown that the presence of a disability can crowd out treatment for medical conditions not necessarily related to the ...
Brian S. Armour, M. Melinda Pitts
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Non-invasive positive pressure ventilation in acute hypercapnic respiratory failure: ten-year’s clinical experience of a Respiratory Semi-Intensive Care Unit (VERSIONE IN ITALIANO) [PDF]
Revista Ciencias de la Salud, 2007 BackgroundAlthough several prospective controlled randomizedtrials demonstrated the success of non-invasive positive pressure ventilation (NIV) in selected cases of acute hypercapnic respiratory failure (IRA) in setting with different care levels ...
Mario Naldi, Raffaele Scala
doaj
Aging and Cancer, EarlyView.This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
Access to Primary Health Care and Health Outcomes: The Relationships between GP Characteristics and Mortality Rates [PDF]
This paper analyses the impact of economic conditions and access to primary health care on health outcomes in Norway. Total mortality rates, grouped into four causes of death, were used as proxies for health, and the number of general practitioners (GPs)
Aakvik, Arild, Holmås, Tor Helge
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Competition and Quality: Evidence from the NHS Internal Market 1991-1999 [PDF]
Payer-driven competition has been widely advocated as a means of increasing efficiency in health care markets. The 1990s reforms to the UK health service followed this path.
Simon Burgess +2 more
core +3 more sources