Results 251 to 260 of about 1,760,346 (311)

Cerebral perfusion pressure trajectories and cumulative exposure metrics predict in-hospital mortality in acute brain injury. [PDF]

Front Med (Lausanne)
Wang J, Li HB, Xu MM, Li WJ, Hang CH, Zhao PL.   +5 more
europepmc   +1 more source

PRMT1‐Mediated LDHA Methylation Drives STAT3 Lactylation to Orchestrate Intestinal Inflammation and Tumorigenesis

Advanced Science, EarlyView.
This study identifies an immunometabolic axis wherein SAM‐driven PRMT1 methylates LDHA, enhancing its activity. The resultant lactate induces STAT3 K709 lactylation, which stabilizes an active conformation to promote STAT3 phosphorylation and IL‐10 expression.
Hui Wang, Mengyu Zhang, Weipeng Gong, Jiaxuan Wu, Junping Zhang, Wenxiu Zhang, Yue Liu, Kui Wang, Canhua Huang, Jun Zhou, Sijin Wu, Yan Li, Tianliang Li   +12 more
wiley   +1 more source

Multi-facility hospital-based surveillance of injury patterns and in-hospital mortality among the adult population in Ghana. [PDF]

J Public Health Res
Idan JS, Stevens JS, Mintah S, Nakua EK.
europepmc   +1 more source

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

Advanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu, Hongjie Dai, Xiaocui Zhong, Qibin Li, Hui Yuan, Yang Yang, Daiyong Huang, Lei Zhang, Rui Ran, Tian He, Yuanzhi Huang, Silas Villas‐Boas, Sergey Tumanov, Richard D. Cannon, Boris Novakovic, Richard Saffery, Yuhao Zhang, Xiaojing Dong, Ting‐Li Han   +18 more
wiley   +1 more source

Association of estimated glomerular filtration rate and in-hospital mortality in patients hospitalized for heart failure: a retrospective cohort study. [PDF]

Front Cardiovasc Med
Aierken Y, Taalaibek Kyzy G, Wei M, Lu Y, Zhang J, Tuerhong Z, Tang B, Zhou X.   +7 more
europepmc   +1 more source

CD4+ Tregs Drive Post‐Ischemic Sprouting Angiogenesis via Endothelial YY1/MAML1 Reactivation

Advanced Science, EarlyView.
ABSTRACT Microvascular complications of diabetes are chronic diseases of small vessels. We previously found that CD4+ regulatory T‐cells (Tregs) are markedly reduced in type 2 diabetes (T2D) after ischemic injury in both mice and humans, and that Treg deficiency in immunodeficient mice impairs vascular regeneration.
Hang Qu, Cheng Kiu Ho, Jitao Liu, Lei Cui, Yangfeng Hou, Cai Liang, Wenchu Ye, Randolph H. L. Wong, Shohei Hori, Bin Zhou, Kathy O. Lui   +10 more
wiley   +1 more source

Burn Injuries in Jordan: A 5-Year Retrospective Analysis of Presentation, Management and Hospital Mortality. [PDF]

Int Wound J
Alshdowh H, Alshraideh JA, Al Qadire M, Abdelrahman H.   +3 more
europepmc   +1 more source

Static and Dynamic Eosinophil Measures and In-Hospital Mortality in Patients with Sepsis: A Retrospective Cohort Study. [PDF]

Medicina (Kaunas)
Mușat F, Andronic O, Bolocan A, Palcău CA, Dobre AM, Ion D, Păduraru DN.   +6 more
europepmc   +1 more source

Predictors of In-Hospital Mortality From Infective Endocarditis in a Resource-Limited, War-Affected Tertiary Center. [PDF]

Rev Cardiovasc Med
Ghalib MA, Al-Kebsi M, Al-Maimoony T, Al-Habeet A.   +3 more
europepmc   +1 more source