Results 91 to 100 of about 2,961,047 (262)

PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao, Lin Gan, Li Lu, Lizhi Ouyang, Yuan Xiong, Fawwaz Al‐Smadi, Guandong Dai, Mohammad‐Ali Shahbazi, Bobin Mi, Mengfei Liu, Guohui Liu   +10 more
wiley   +1 more source

The Spectrum of Clinical Pharmacy Services in a Non-University Hospital—A Comprehensive Characterization Including a Risk Assessment for Drug-Related Problems and Adverse Drug Reactions

Pharmacy
Background: Clinical pharmacy services (CPS) have been shown to confer significant advantages in patient care. It remains to be clarified how CPS resources are allocated across routine care settings.
Olaf Zube, Wiebke Schlüter, Johanna Dicken, Jan Hensen, Thilo Bertsche   +4 more
doaj   +1 more source

Water‐Activated Phospholipid Phase‐Separation Gel as an Immunomodulatory Anti‐Adhesion Barrier for Postoperative Adhesion Prevention

Advanced Healthcare Materials, EarlyView.
A water‐activated phospholipid phase‐separation gel is repurposed as a drug‐free surgical barrier for postoperative adhesion prevention. Propylene glycol promotes rapid lamellar gel reinforcement, prolonged local retention, and tissue coverage, while phosphatidylcholine‐mediated immunomodulation suppresses inflammatory and fibrotic responses. This dual‐
Jong‐Ju Lee, Yulseung Sung, Yeji Kim, Heesang Yang, Suyeon Pyo, Byeol Yun, Sung‐Joo Hwang   +6 more
wiley   +1 more source

Extemporaneous Compounding, Pharmacy Preparations and Related Product Care in the Netherlands

Pharmaceutics
Background/Objectives: In many parts of the world, pharmacists hold the primary responsibility for providing safe and effective pharmacotherapy. A key aspect is the availability of appropriate medicines for each individual patient.
Herman J. Woerdenbag, Boy van Basten, Christien Oussoren, Oscar S. N. M. Smeets, Astrid Annaciri-Donkers, Mirjam Crul, J. Marina Maurer, Kirsten J. M. Schimmel, E. Marleen Kemper, Marjolijn N. Lub-de Hooge, Nanno Schreuder, Melissa Eikmann, Arwin S. Ramcharan, Richard B. Lantink, Julian Quodbach, Hendrikus H. Boersma, Oscar Kelder, Karin H. M. Larmené-Beld, Paul P. H. Le Brun, Robbert Jan Kok, Reinout C. A. Schellekens, Oscar Breukels, Henderik W. Frijlink, Bahez Gareb   +23 more
doaj   +1 more source

Nuclear Pore Mechanotransduction in Oncology: A Structural Axis of Vulnerability for Targeted Intervention

Advanced Materials, EarlyView.
Cancer‐associated NPC remodeling creates a high‐flux, low‐stringency nuclear state that supports malignant adaptation but increases mechanical fragility. Targeting the FG‐barrier or NPC scaffold may drive mechanostat failure, envelope rupture, DNA damage, and loss of nuclear integrity.
Sílvio Terra Stefanello, Caren Rigon Mizdal, Aline Franzen da Silva, Yun Qian, Wei‐En Yuan, Victor Shahin   +5 more
wiley   +1 more source

Identifying the Risk Factors of Medication Errors in a Tertiary Hospital in Iran

Journal of Research in Pharmacy Practice
Objective: The services of pharmacists in the hospital go beyond the distribution of medicine, and today, it means the role of pharmacists in the optimal use of medicines by patients and improving their health outcomes. The purpose of this research is to
Saeed Mohammad Soleymani, Mahdi Mirheydari Peykani, Sara Salarian, Alireza Manafi Rasi, Alireza Heidarian, Hadi Esmaily   +5 more
doaj   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

DESIGNING AN E-KANBAN SYSTEM TO IMPROVE DRUG AVAILABILITY AND MINIMISE INVENTORY WASTE AT THE HOSPITAL PHARMACY INSTALLATION

J@ti Undip: Jurnal Teknik Industri
In an effort to provide a high level of service to hospitals, pharmaceutical installations are often faced with problems in monitoring and determining adequate drug supply levels to respond to demand, both from outpatient and inpatient units.
Sriyanto Sriyanto, Rinawati Dyah Ika
doaj   +1 more source

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

Advanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin, Yimo Yan, Nikola Cesarovic, Simone Schuerle   +3 more
wiley   +1 more source

Intelligent Micro/Nanorobots for Targeted Interventional Therapy: From Bench to Clinic

Advanced Robotics Research, EarlyView.
Zirui Zhang et al. reviewed the application and challenges of mobile nanomachines in interventional therapy. By converting exogenous energy, including chemical, magnetic, optical, and ultrasonic sources, into mechanical forces, micro/nanorobots (MNRs) enable precise actuation at unprecedented scales. Evolving far beyond traditional drug delivery, these
Zirui Zhang, Yu Dong, Yongsheng Du, Rui Gao, Lin Zhang, Fei Tong   +5 more
wiley   +1 more source