Results 51 to 60 of about 396,938 (291)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Prevalence, Characteristics, and Challenges of Compounded Sterile and Non-sterile Pharmaceutical Preparations in Tabuk Hospitals: Across-sectional Survey Study

Bulletin of Pharmaceutical Sciences. Assiut University
Pharmaceutical extemporaneous compounding is limited by several challenges related to the lack of resources or trained pharmacists. This study aimed to investigate the prevalence, features, and factors influencing extemporaneous compounding in Tabuk ...
Mostafa Mostafa A. Sayed Ali ٍSayed Ali, Ghareb Soliman, Amani Alfaiafi, Asma Alwabisi, Yara Aljohani, Sara Aljadrawi   +5 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Dispensation of outpatient hospital medicines by hospital only versus hospital-community pharmacies collaboration: a cross-sectional study and survey of patient’s satisfaction

Frontiers in Public Health
GoalTo describe the experience of a dispensing model of outpatient hospital medicines (OHM) via collaboration of hospital and community pharmacies, and to explore patient satisfaction with the strategy as compared with the hospital pharmacy only service ...
Olivia Ferrández, Olivia Ferrández, Santiago Grau, Santiago Grau, Elena Colominas-González, Elena Colominas-González, María Eugenia Navarrete-Rouco, Nuria Carballo-Martínez, Marta De Antonio-Cuscó, Xènia Fernández-Sala, Laura Rio-No, Oscar Fando Romera, Maria Berzosa Malagon, Sergio Pineda Rodriguez, Noelia Torres Rius, Xavier Duran-Jordà, Cristina Rodríguez-Caba, Jordi Casas-Sánchez, Félix Caro Herranz, Caridad Pontes-García   +19 more
doaj   +1 more source

Refer-To-Pharmacy: Pharmacy for the Next Generation Now! A Short Communication for Pharmacy

Pharmacy, 2015
Refer-to-Pharmacy is the first fully integrated hospital to community pharmacy referral system. This article explains the importance of these referrals for patients and health economies to improve medicines optimisation, and how Refer-to-Pharmacy works ...
Alistair Gray
doaj   +1 more source

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

Pilot Implementation of Falsified Medicines Directive in Hospital Pharmacy to Develop Best Practices for Medicine Decommissioning Process

Pharmacy, 2020
Background: The introduction of a medicines verification and decommissioning system into the hospital pharmacy may result in an increased workload for pharmacy staff.
Piotr Merks, Damian Świeczkowski, Mikołaj Zerhau, Anna Gawronska, Anna Kowalczuk, Klaudiusz Gajewski, Ralf Däinghaus, Miłosz Jaguszewski, David Brindley   +8 more
doaj   +1 more source

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel, Timothy P. Siejka, Cassandra Marotta, Josh J. Y. Lee, Kelly Bertram, Terence J. O'Brien, Meng Law, Lucy Vivash, Ian H. Harding   +8 more
wiley   +1 more source

UH Pharmacy Update

, 1987
Newsletter for University Hospital practitioners, providing updates on pharmaceutical ...
Laohapornsvan, Ming, Scanlin, Lorena, The University Hospital, Department of Pharmacy, Yeh, Jen Jen, Boston University Medical Center, Rich, Darryl S., Mu-Chow, Kimberly, Scanlin, Lorena J.   +7 more
core   +2 more sources

Desirable Traits of Hospital Pharmacy Preceptors and Residents

, 2001
INTRODUCTIONThe British Columbia Hospital Pharmacy Residency Program has been in existence since 1970. It has expanded since its inception and now encompasses 7 hospitals, which offered a total of 17 residency positions during the 1999/2000 residency ...
Kanji, Zahra, Hamilton, Don, Hill, David
core   +1 more source