Results 201 to 210 of about 8,717,419 (341)

Spatiotemporal Sequential Delivery of Chidamide Regulates Macrophage Reprogramming in Lymphoma Microenvironment Through HDACs‐STAT3 Pathway

Advanced Science, EarlyView.
Our study identifies the HDACs‐STAT3 axis as key regulator for M2 macrophage accumulation in DLBCL. We developed Chid@M2pep‐EVs/TP, a pH‐responsive drug delivery system for M2 macrophage specific chidamide administration. By coupling M2‐targeted chidamide with EVs‐mediated delivery, this system reprograms M2 to M1 via HDAC inhibition and STAT3 ...
Bo Dai, Shuo Wang, Xiaotong Peng, Kunpeng Wu, Mengyao Wu, Zhaoning Lu, Haoshu Zhong, Xiaohan Qian, Shuiyi Tan, Hui Yang, Tanlezi Sun, Jing Wang, Jie Zhang, Hua Jiang, Yin Tong, Tong Chen   +15 more
wiley   +1 more source

Exploring Challenges and Opportunities in Hospital Disaster Preparedness: A Qualitative Study on the Perspectives of Hospital Incident Command System Members

Risk Management and Healthcare Policy
Prinka Singh,1,2 Sujan Sapkota,3 Nebil Achour,4 Luca Ragazzoni,1,2 Hamdi Lamine1,5 1CRIMEDIM-Center for Research and Training in Disaster Medicine, Humanitarian Aid and Global Health, Università Del Piemonte Orientale, Novara, 28100, Italy; 2Department ...
Singh P, Sapkota S, Achour N, Ragazzoni L, Lamine H   +4 more
doaj  

Adapting Neurology Residency: A Case Study and Practical Guide for Accommodations for a Disabled Resident. [PDF]

Neurol Educ
Pisano TJ, Stein LA.
europepmc   +1 more source

High Humidity Exacerbates Psoriasiform Skin Disease Relapse by Increasing Tissue‐Resident Memory T Cells via Altering Skin Microbiota

Advanced Science, EarlyView.
We demonstrated that high humidity worsened psoriasis relapse in murine psoriasiform skin inflammation by increasing skin‐resident memory CD8+ cells via upregulating IL‐15Rα on keratinocytes. The increases in IL‐15Rα and memory CD8+ cells were attributed to S. nepalensis and its metabolite ADMA in skin exposed to high humidity.
Chun‐Ling Liang, Yuchao Chen, Chuanjian Lu, Huazhen Liu, Fenglian Qin, Sisi Dai, Feifei Qiu, Haiming Chen, Weihui Lu, Jonathan S. Bromberg, Zhenhua Dai   +10 more
wiley   +1 more source

From Hospital to Home: Enhancing Family Support with MIGYN (Mitra Interaktif Ginekologi), an AI-Based Discharge Planning Chatbot. [PDF]

J Multidiscip Healthc
Maryati I, Ermiati E, Natasya W, Hasanah A, Irmala N, Susanti S, Atikah A, Yulianti DEF, Abdullah KL.   +8 more
europepmc   +1 more source

Hospital planning for weapons of mass destruction incidents.

Journal of Postgraduate Medicine, 2006
Ronald W. Perry, M. Lindell
semanticscholar   +1 more source

NRS-4900 | Report of the State Medical Planning Committee on hospital accommodation [State Medical Planning Committee]

The report contains the following information in 4 stages: classification of hospitals; report of the service facilities in hospitals; report on the figure of hospital patients who could be discharged in an extreme medical emergency; and report on the ...

core  

N, S Co‐Doped Carbon Quantum Dots‐Riboflavin Composite Photosensitizers for Enhanced Iontophoresis‐Assisted Corneal Cross‐Linking

Advanced Science, EarlyView.
This study explores the use of N, S co‐doped carbon quantum dots (NS‐CQDs) as carriers for riboflavin, creating NS‐CQDs‐RF composite photosensitizers. These composites improve riboflavin absorption, enhance ROS generation efficiency, and preserve corneal epithelium integrity.
Tinghong Xu, Yong Liu, Wenjing Zhang, Qiuruo Jiang, Yi Jin, Liangzheng Lin, Lumeng Wang, Zhanhao Gu, Mimi Lin, Shihao Chen   +9 more
wiley   +1 more source

Association between discharge planning department staffing levels and the average length of stay in acute care wards: a nationwide cross-sectional study in Japan. [PDF]

BMJ Open
Machida A, Kashiwagi M.
europepmc   +1 more source

TRMT6‐Mediated m1A Modification of CDK9 mRNA Is a Dual‐Pronged Pathogenic Driver for HBV‐Related Hepatocellular Carcinoma

Advanced Science, EarlyView.
TRMT6‐mediated m1A modification in CDK9 mRNA enhances its mRNA stability and translation efficiency, thereby increasing the protein levels of CDK9. Upregulated CDK9 promotes the progression of HCC by elevating the levels of oncogenic factors including p‐STAT3, MCL1, and BCL‐2. On the other hand, CDK9 phosphorylates TARDBP at Ser254 to activate HBV core
Rui Zhang, Dandan Zong, Rui Liu, Yubo Wang, Qingqing Gu, Yao Yao, Wenfang Zheng, Mengmeng Yuan, Simeng Wang, Rongrong Cui, Daxu Li, Siwen Dang, Peng Hou   +12 more
wiley   +1 more source