Results 121 to 130 of about 1,953,126 (302)

Changes in patterns of multimorbidity and associated with medical costs among Chinese middle-aged and older adults from 2013 to 2023: an analysis of repeated cross-sectional surveys in Xiangyang, China

Frontiers in Public Health
BackgroundMultimorbidity has become a major public health problem among Chinese middle-aged and older adults, and the most costly to the health care system.
Changyu Ju, Hongjia Liu, Yongxiang Gong, Meng Guo, Yingying Ge, Yuheng Liu, Rui Luo, Meng Yang, Xiuying Li, Yangwenhao Liu, Xiangbin Li, Tiemei He, Xiaodong Liu, Chunrong Huang, Yihua Xu, Juming Liu   +15 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Penerapan Manajemen Mutu Pelayanan di Unit Rekam Medis Rumah Sakit PKU Muhammadiyah Surakarta [PDF]

, 2016
The presence of medical records on a hospital is very important as a source of information derived from medical records. hence the need for good quality management in penggelolaan medical record as the basis for planning and assessing the performance of ...
, Sri Sugiarsi, SKM, M.Kes, Susanto, Anton   +1 more
core  

Development of a hospital frailty risk score for community-dwelling older adults using data from electronic hospital records in South Korea. [PDF]

PLoS One, 2023
Kim HS, Kim J, Bae G.
europepmc   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Effects of communication, trust, and respect on shared decision-making: insights from healthcare providers in Chinese public hospitals

Frontiers in Medicine
BackgroundShared decision making (SDM) could significantly enhance health knowledge, treatment adherence, and doctor-patient relationship, but multifaceted barriers have influenced the implementation of SDM worldwide.
Lu Chen, Huijun Chu, Hui Wang, Liang Du, Yumeng Gao, Jie Shen   +5 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

O Sistema de Informação Hospitalar e sua aplicação na saúde coletiva

Cadernos de Saúde Pública
O trabalho teve como objetivo levantar a produção científica das aplicações dos dados do Sistema de Informação Hospitalar do SUS (SIH/SUS) em análises de questões relevantes de Saúde Coletiva. Para a busca de artigos publicados em revistas científicas no
Sonia Azevedo Bittencourt, Luiz Antonio Bastos Camacho, Maria do Carmo Leal   +2 more
doaj  

Distribution of Cancer and Cancer Screening and Treatment Services in Lagos: A 10-Year Review of Hospital Records. [PDF]

JCO Glob Oncol, 2022
Omosun A, Abayomi A, Ogboye O, Lajide D, Oladele D, Popoola A, Banjo AA, Chugani B, Mabadeje B, Abdur-Razaak H, Wellington O, Andu L, Adepase A, Adesina F, Olonire O, Fetuga A, Onasanya O, Awosika F, Folarin-Williams O, Anya SE.   +19 more
europepmc   +1 more source