Results 41 to 50 of about 150,347 (295)

Analysis of the use of imipenem at a University Hospital following the restructuring of an antimicrobial audit system

Brazilian Journal of Infectious Diseases
This study analyzed the use pattern of imipenem following the restructuring of the antimicrobial audit system at a University Hospital. It was an observational study before and after the restructuring of the antimicrobial audit system in a University ...
N.P. Souza, A.C.B. Noblat, L. Noblat
doaj   +1 more source

Suggestions for the restructuring of hanseniasis institutions in Brazil

Hansenologia Internationalis, 1976
After seeking to establish the fact that the structures of institutions for the treatment of Hansen's disease are normally obsolete, archaic, and foster paternalism and sentimentality, the author proposes a restructuring of these institutions with the ...
O. CRUZ
doaj   +1 more source

Bifidobacterium Breve Yang08 Alleviates Atopic Dermatitis By Enriching Akkermansia Muciniphila and Inhibiting Neutrophil Extracellular Traps Formation In Mice

Advanced Science, EarlyView.
A novel Bifidobacterium breve strain, Yang08, is isolated to counter its depletion in atopic dermatitis. In mice, live Yang08 requires an intact gut microbiota to exert protection, specifically enriching Akkermansia muciniphila and potently inhibiting pathogenic neutrophil activation and NETosis in the skin.
Yanqiang Shi, Shuang He, Chengyi Li, Hung Chan, Zhenfeng Liu, Bin Yang, Qing Li   +6 more
wiley   +1 more source

‘Rogue’ Social Workers: The Problem with Rules for Ethical Behaviour [PDF]

, 2014
This article explores one aspect of increased managerialism, the impact of the expansion of rules in organizations. Discussing findings from a recent large-scale Canadian research project with social workers, this paper addresses some of the effects of ...
Taylor, Stephanie, Weinberg, Merlinda
core  

Biomimetic Membrane Interface Technologies for Detection and Isolation of CTCs and EVs: Advances and Opportunities in Liquid Biopsy

Advanced Science, EarlyView.
Biomimetic membrane interface engineering constructs functionalized detection platforms by integrating natural cell membranes, synthetic lipids, or hybrid membranes. This strategy effectively reduces background interference and enables efficient target capture and analysis, showing broad applications in circulating tumor cell separation, extracellular ...
Duo Liu, Jie Yu, Jingxue Li, Yixue Chen, Mengle Peng, Yifan Xu, Yongjun Wu, Lihua Ding, Sitian He   +8 more
wiley   +1 more source

THE RESULTS OF THE FIRST DECADE OF WORK IN THE SYSTEM OF FMBA OF RUSSIA. PROSPECTS AND ACHIEVEMENTS OF SOUTH REGIONAL MEDICAL CENTER

Клиническая практика, 2017
Thе article summarizes some results of work of the Southern Regional Medical Centre FMBA of Russia, analyses the results of the carried-out work for organizational structure improvement, restructuring of hospital bedspace and increasing the efficiency of
V S Krishtopin, S A Pleskachev, I I Osetrova   +2 more
doaj   +1 more source

Do Reductions in Medicaid/SCHIP Enrollment Increase Emergency Department Use Among Low-Income Persons? [PDF]

, 2007
Outlines estimates of the impact on emergency department visits by the uninsured and the overall low-income population if Medicaid and State Children's Health Insurance Program enrollment and physicians' acceptance rates of Medicaid patients were to ...
Melanie Napier, Peter J. Cunningham
core  

Asymmetric Cu─N─Ru Bridgedsite Nanozyme‐Loaded Injectable Thermogel Boosts Cuproptosis‐Like Death for Multidrug‐Resistant Urinary Tract Infections

Advanced Science, EarlyView.
To address multidrug‐resistant urinary tract infections (MDR‐UTIs), we developed Cu‐ZIF8‐Ru nanozyme featuring an asymmetric Cu─N─Ru catalytic site. This unique structure enhances multienzyme‐mimetic activity, eradicating resistant bacteria by inducing a cuproptosis‐like death pathway through intracellular Cu2+ accumulation and energy depletion.
Guanlin Li, Shike Zhang, Jinggong Liu, Xin Wang, Heng Wang, Hongcan Yang, Yuhao Zhou, Wen Liu, Hongxing Liu, Wenqi Wu   +9 more
wiley   +1 more source

Modelagem e análise de um novo centro cirúrgico para um hospital em crescimento: uma abordagem baseada em simulação Modeling and analysis of a new surgical center for a growing hospital: a simulation-based approach

Production, 2009
Uma instituição hospitalar precisa de constante aperfeiçoamento para ser eficiente no seu principal negócio: o bem-estar do ser humano. Este artigo descreve um projeto realizado no Hospital Universitário da PUCPR, cujo principal objetivo é avaliar ...
Élcio Douglas Joaquim, Guilherme Ernani Vieira   +1 more
doaj   +1 more source

PROTAC‑Mediated HMGCR Depletion Reprograms Lipid Metabolism in Breast Cancer to Potentiate Photoimmunotherapy via Ferroptosis

Advanced Science, EarlyView.
This work introduces a study that identifies HMGCR as a novel target in TNBC and develops a light‐gated PROTAC nanomedicine. Upon irradiation, this agent selectively degrades HMGCR, reprogramming lipid metabolism to induce ferroptosis and potent antitumor immunity, thereby significantly enhancing photoimmunotherapy efficacy.
Tong Su, Guang Li, Yudong Guan, Qi Tian, Youzhi Qi, Yanqiu Zhang, Wenqian Wei, Xinxin Duan, Jiaxin Rui, Hongyan Zhu, Zengping Lin, Changchuan Xie, Zheni Xu, Yaying Wu, Xin Peng, Zhenjie Wang, Kun Chen, Xiaoyan Xin, Bing Zhang   +18 more
wiley   +1 more source