Results 61 to 70 of about 88,107,133 (294)

Nationwide Survey of Association Between Fever and Epileptic Seizure in CDKL5 Deficiency Disorder Revealed Therapeutic Implications

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective CDKL5 deficiency disorder (CDD) is a rare, severe developmental and epileptic encephalopathy. There is a pressing need to develop effective and sustainable therapeutic strategies. We aimed to investigate the causal association between febrile episodes and epileptic seizures for therapeutic implications in CDD patients.
Siyi Wang   +13 more
wiley   +1 more source

Real‐World Trends in Prenatal Antirheumatic Drug Utilization in Ontario, Canada: A Cross‐Sectional Time‐Series Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective This study aimed to describe real‐world trends in preconception and prenatal use of antirheumatic drugs among pregnant individuals with rheumatic diseases in Ontario, Canada. Methods We conducted a time‐series analysis using repeated cross‐sectional data to examine annual patterns of disease‐modifying antirheumatic drug (DMARD) use among ...
Shenthuraan Tharmarajah   +6 more
wiley   +1 more source

Effectiveness of transitional care program in older adults with heart failure: a systematic review and meta-analysis of randomised controlled trials

open access: yesBMC Geriatrics
Background Heart failure leads to adverse clinical and patient-reported outcomes. Its prevalence has increased markedly among adults aged 60 years and over.
Ayşe Yücesan   +2 more
doaj   +1 more source

Consultancy to progress hospital in the home care provision: Final report, CHERE Project Report No 13 [PDF]

open access: yes
In July 1998, the Commonwealth Department of Health and Family Services commissioned the Centre for Health Economics Research and Evaluation (CHERE) to identify and document Hospital in the Home (HITH) care models nationally and internationally.
Marion Haas   +3 more
core  

Health Care Use Among Patients Presenting to Emergency Department for Gout Flares in Ontario, Canada: A Population‐Based Health Systems Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective We characterized emergency department (ED) gout visits and identified patient characteristics and health services patterns contributing to ED presentations. Methods We conducted a population‐based study of ED gout visits in Ontario, Canada, between 2014 and 2023.
Timothy S. H. Kwok   +7 more
wiley   +1 more source

Outpatient Parenteral Antimicrobial Therapy in a Tertiary Hospital in France: A Description of Service Models and Costs

open access: yesAntibiotics
Background/Objectives: Outpatient parenteral antimicrobial therapy (OPAT) has been implemented throughout the world for the treatment of most infections.
Espérie Burnet   +10 more
doaj   +1 more source

From Cell‐Derived Vesicles to Hybrid Nanovectors: Biological Membranes as Functional Blueprints for Gene Delivery

open access: yesAdvanced Healthcare Materials, EarlyView.
Biologically derived and hybrid nonviral nanovectors are examined as distinct but convergent design approaches. Integrating synthetic components with biologically functionalized membranes allows efficient interactions with complex cellular environments.
Clara Baldari   +10 more
wiley   +1 more source

Transition from in-hospital ventilation to home ventilation: process description and quality indicators

open access: yesGMS German Medical Science, 2017
The current demographic development of our society results in an increasing number of elderly patients with chronic diseases being treated in the intensive care unit.
Kastrup, Marc   +7 more
doaj   +1 more source

Hospital in the Home in NSW, CHERE Project Report No 16 [PDF]

open access: yes
Hospital in the home ...
Marion Haas   +2 more
core  

Wearable Morphology‐Adaptive in‐Ear Device With Active Cleansing Capability for Multimodal Health Monitoring

open access: yesAdvanced Materials, EarlyView.
We present SCIENCE, an in‐ear multimodal physiological monitor featuring two key innovations. Water‐triggered morphological expansion (a 2‐mm cylinder to a 9‐mm spindle) achieves conformal adaptation across complex canal geometries. Simultaneously, active biofouling mitigation disrupts cerumen barriers, reducing sensor‐skin impedance by 20%.
Shuyun Zhuo   +3 more
wiley   +1 more source

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