ABSTRACT Management of cerebral vasculopathy in sickle cell anemia (SCA) includes standard‐care, that is, chronic transfusion (CT) or hydroxyurea, and hematopoietic cell transplantation (HCT). DREPAGREFFE‐1 (December 2010/June 2013), a French multicenter trial, was the first prospective trial comparing standard‐care to match sibling donor (MSD)‐HCT in ...
Francoise Bernaudin +40 more
wiley +1 more source
Dengue hospitalizations in Brazil: Forecasting with climatic and physicians' digital search data under real-world reporting delays. [PDF]
Palmer DQ +6 more
europepmc +1 more source
ABSTRACT Talquetamab is a GPRC5D × CD3 bispecific antibody approved for relapsed/refractory multiple myeloma (RRMM). This is the first real‐world study to comprehensively report muco‐cutaneous toxicities, infections, and efficacy of talquetamab in 151 patients across five countries with the longest follow‐up reported enabling better efficacy and ...
Murali Janakiram +94 more
wiley +1 more source
GENERATIVE AI TOWARDS A COMPARATIVE ANALYSIS OF HOSPITALIZATION RATES AMONG PATIENTS WITH ULCERATIVE COLITIS TREATED WITH INFLIXIMAB, VEDOLIZUMAB, AND TOFACITINIB IN THE PUBLIC HEALTHCARE SYSTEM IN BRAZIL: A NATIONWIDE STUDY. [PDF]
Valverde DA +4 more
europepmc +1 more source
Characteristics of long stay home care clients' acute care use who live with frailty in Alberta, Canada: A retrospective cohort study. [PDF]
Rasiah J +4 more
europepmc +1 more source
Checking into the hospital? Don\u2019t check out with a blood clot!
Did you know that getting a blood clot from a hospitalization, surgery, or other healthcare treatment or procedure (called healthcare-associated venous thromboembolism or HA-VTE for short) is a significant, costly and growing public health problem? It is!
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Clinically Relevant Bleeding in Individuals With Cancer: Insights From a Nationwide Cohort Study
ABSTRACT Cancer care is often complicated by coagulopathy leading to thrombosis and bleeding. While venous thromboembolism (VTE) has been extensively studied, bleeding remains an underestimated threat. To address this knowledge gap, we leveraged the Epic Cosmos database to determine the impact of cancer‐associated clinically relevant bleeding (CRB) in ...
Ming Y. Lim +11 more
wiley +1 more source
Oral Health and Gut-Targeted Microbial Marker Changes Associated with Prolonged Hospitalization in Cardiac Patients: An Integrative Risk Analysis. [PDF]
Grigore I +9 more
europepmc +1 more source
ABSTRACT The transformation/transcription domain‐associated protein (TRRAP) gene encodes a large multidomain protein, a member of the phosphatidylinositol 3‐kinase‐related kinase (PIKK) family. TRRAP is a component of the histone acetyltransferase (HAT) complex, and it plays an important role in gene transcription, DNA repair, and cell‐cycle regulation.
Roseli Maria Zechi‐Ceide +10 more
wiley +1 more source
Population aging and changing hospitalization risks in Germany: a decomposition of changes in inpatient cases, 2005-2021. [PDF]
Piereth AK, Rau R, Ebeling M.
europepmc +1 more source

