Results 191 to 200 of about 704,466 (266)

Virus‐Mediated Self‐Assembly of Functional Cyclodextrins for Antiviral Inhibition

Angewandte Chemie, EarlyView.
A sialic acid (SA)‐functionalized cyclodextrin (CD) self‐assembles on SARS‐CoV‐2 through ligand–receptor recognition, nucleating cooperative supramolecular polymer growth that blocks infection. The adaptive assembly requires both ligand binding and host–guest polymerization, remains active across variants, and can be tuned by coassembly, establishing ...
Pedro J. Hernando, Laora Boulo, Léonid Lavnevich, Elisa Teyssou, Stéphane Marot, Adélie Gothland, Jean‐Michel Guigner, Anne‐Geneviève Marcelin, Mickaël Ménand, Vincent Calvez, Matthieu Sollogoub   +10 more
wiley   +2 more sources

Comparable Infection Risk of Ocrelizumab and Rituximab in Multiple Sclerosis in a Nationwide Swedish Cohort Study

Annals of Neurology, EarlyView.
In multiple sclerosis (MS), anti‐CD20 therapies have been associated with increased infection risk, but whether this risk differs between rituximab and ocrelizumab is not known. Using a nationwide cohort, we studied infection risk and relapse outcomes among 16,872 treatment episodes with rituximab, ocrelizumab, or other disease‐modifying therapies ...
Thomas Frisell, Sebastian Hedberg, Fredrik Piehl   +2 more
wiley   +1 more source

Diabetes and the Metabolic Syndrome as Drivers of Neurodegeneration: Convergent Mechanisms Linking Peripheral Neuropathy and Dementia

Annals of Neurology, EarlyView.
The metabolic syndrome, a state of progressive metabolic dysfunction, injures the peripheral and central nervous systems, promoting peripheral neuropathy (PN) and cognitive impairment (CI), respectively. We posit PN and CI are connected in the metabolic syndrome framework, built on the premise that neurons, whether in the peripheral or central nervous ...
Masha G. Savelieff, David L. Bennett, Troels S. Jensen, Eva L. Feldman   +3 more
wiley   +1 more source

Clinical impact of an EHR-integrated hyperkalemia management system: a real-world study of 10,934 episodes. [PDF]

Ren Fail
Lyu G, Zhang F, Fan X, Li R, Zhou X.
europepmc   +1 more source

Machine learning evaluation of racial and ethnic inclusion under alternative cost-based approaches to Medicare Medication Therapy Management eligibility. [PDF]

J Manag Care Spec Pharm
Tsang CCS, Cui Y, Cushman WC, Wang J.
europepmc   +1 more source

Assessment of Functioning and Disability Based on WHODAS 2.0 and Related Factors Among People Aged 80 and Over Hospitalized in a Geriatric Ward in Southeastern Poland. [PDF]

Med Sci Monit
Brożonowicz J, Sozańska A, Sozański B, Wilmowska-Pietruszyńska A, Orzech-Janusz E, Wiśniowska-Szurlej A.   +5 more
europepmc   +1 more source

Artificial Neural Network Driven Computational Modeling of Naegleria fowleri Epidemics Using Variational Optimization

Advanced Physics Research, EarlyView.
ABSTRACT This study presents a mathematical framework to analyze the transmission dynamics of an amoeba‐induced central nervous system infection. The population is divided into compartments including susceptible, exposed, infected, quarantined, hospitalized, recovered, protected, and deceased.
Wakeel Ahmed, Areej Yaseen, Ghulamullah Saeedi, Shakeel Ahmed   +3 more
wiley   +1 more source

Prompt and Intensive Antiviral Chemoprophylaxis in Nursing Home Influenza Outbreaks.

JAMA Intern Med
Silva JBB, Hsieh HT, Howe CJ, Gravenstein S, Reich LA, Zullo AR.   +5 more
europepmc   +1 more source

Application of an AI-Based Pediatric Early Warning Score in the Pediatric Emergency Department: Cross-Sectional Study. [PDF]

JMIR Form Res
Xie W, Shi X, Peng M.
europepmc   +1 more source

Nontobacco Nicotine Dependence Is Associated With Perioperative Complications and Repeat Surgery After Arthroscopic Rotator Cuff Repair

Arthroscopy, EarlyView.
Purpose To compare perioperative complications and revision surgery rates between following primary rotator cuff repair among patients with nontobacco nicotine dependence (NTND), no nicotine dependence, and traditional tobacco‐related nicotine dependence.
Samuel A. Florentino, Alexander N. Berk, Logan M. Good, Jeremy M. Adelstein, Robert J. Wetzel, George Ochenjele, Joshua K. Napora   +6 more
wiley   +1 more source