Results 151 to 160 of about 445,978 (269)

Comparison of patient, hospitalization and center characteristics from the EMMY centers, IFM centers, and all multiple myeloma centers in France. [PDF]

Clin Hematol Int
Olivier D, Garlantezec R, Perrot A, Macro M, Royer B, Belhadj Merzoug K, Vincent L, Chalopin T, Frenzel L, Bobin A, Mohty M, Touzeau C, Zunic P, LE Calloch R, Lachenal F, Roussel M, Richez-Olivier V, Fleury J, Loppinet E, Leduc I, Tiab M, Delaunay J, Gutnecht J, Corm S, Bazin F, McKelvie-Sebileau P, Rollet S, Mouton H, Gibel L, Louni C, Boumendile A, Hulin C.   +31 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Predictors of excess length of stay among tuberculosis patients at Highland Hospital, Alameda County, California, 2018-2022. [PDF]

Antimicrob Steward Healthc Epidemiol
Hollingsworth E, Willkom J, Marusinec R, Yette E, Chitnis A, Moazed F.   +5 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Brazilian Portuguese Adaptation of the Updated Clinical Frailty Scale: Cross-Cultural Adaptation, Reliability, and Convergent Validity in Hospitalized Older Adults. [PDF]

J Aging Res
Rodrigues MK, Jenkins RA, Malta V, Lopes CAC, Oliveira MF.   +4 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Correction: Clinical outcomes in hospitalized patients with community-acquired pneumonia: A comprehensive analysis of associated factors. [PDF]

PLoS One
PLOS One Staff.
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Patients With Berardinelli-Seip and Silver-Russell Syndromes Hospitalized due to Coronavirus Disease (COVID)-19 in Brazil: A Four-Year Case Report Profile. [PDF]

Case Rep Infect Dis
Marques LFA, Silva AEF, Costa PT, Mello LS, Dos Santos VS, Marson FAL.   +5 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source