Results 161 to 170 of about 447,529 (219)

Longitudinal Study of Subsequent Wheezing/Asthma Risk Among Children Hospitalized for Acute Respiratory Infections - Yichang City, Hubei Province, China, 2017-2024. [PDF]

China CDC Wkly
Qin Q, Wang Q, Wang S, Wang L, Sun J, Li G.   +5 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

The Importance of Learning Skills as Perceived by Adolescents in a Hospital School in Romania vs. Their Non-Hospitalized Peers. [PDF]

Contin Educ
Jianu MM, Niță E, Benchea M.
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Microbial product translocation and mortality in adults hospitalised with HIV-associated tuberculosis: a prospective observational cohort study

Schutz C, Queiroz A, Mota T, Ward A, Barr D, Janssen S, Shey M, Wilkinson R, Wilkinson K, Burton R, Lelouvier B, Andrade B, Meintjes G.   +12 more
europepmc   +1 more source

Stage of Disease Among Hospitalized Persons Living With Dementia: A Multisite Study. [PDF]

J Am Med Dir Assoc
Lynch DH, Lynch ME, Wessell KL, Lin FC, Toles M, Mitchell SL, Hanson LC.   +6 more
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Post-acute organ complications within one year following COVID-19 hospitalization and related socioeconomic inequalities. [PDF]

Nat Commun
Cavillot L, Van den Borre L, Ghattas J, Boiy E, Af van Loenhout J, Hubin P, Smith P, De Smedt D, Vanthomme K, Gadeyne S, De Pauw R, Speybroeck N, Devleesschauwer B.   +12 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Influenza infection influencing factors and direct economic burden - A study based on hospitalized cases of severe acute respiratory infection (SARI). [PDF]

Hum Vaccin Immunother
Xu W, Sun L, Wang J, Yin H, Li C, Pei Y, Song S, Zhang R, Kou Z, Wang T, Liu T.   +10 more
europepmc   +1 more source