Results 111 to 120 of about 10,742,565 (331)

Endoglin mediates the tumor‐ and metastasis‐promoting traits of stromal myofibroblasts in human breast carcinomas

Molecular Oncology, EarlyView.
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo, Yoshihiro Mezawa, Zixu Wang, Ahmet Acar, Yasuhiko Ito, Atsushi Takano, Yohei Miyagi, Tomoyuki Yokose, Toshinari Yamashita, Yataro Daigo, Takuya Shirakihara, Akira Orimo   +11 more
wiley   +1 more source

The Effects of Cardiac Specialty Hospitals on the Cost and Quality of Medical Care [PDF]

The recent rise of specialty hospitals -- typically for-profit firms that are at least partially owned by physicians -- has led to substantial debate about their effects on the cost and quality of care. Advocates of specialty hospitals claim they improve
Daniel P. Kessler, Jason R. Barro, Robert S. Huckman   +2 more
core  

Small power and lighting load time series data for 27 departments across 8 UK hospitals [PDF]

, 2016
The electricity consumption of 27 departments was measured across 8 medium to large General Acute hospitals in England (largely by the authors, some data was donated and authorised for publication by the respective hospitals). The departments fall into 6
Li, M, Morgenstern, P, Raslan, R, Ruyssevelt, P, Wright, A   +4 more
core   +1 more source

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source

Morbidade hospitalar em município da região Sul do Brasil em 1992

Revista de Saúde Pública
Com o objetivo de caracterizar a morbidade hospitalar, foi analisada uma amostra constituída por 2.518 internacões de 8 hospitais gerais do Município de Maringá-PR, Brasil, em 1992, segundo as variáveis: diagnóstico, sexo, idade, procedência, fonte de ...
Thais A. F. Mathias, Maria Lúcia de M. S. Soboll   +1 more
doaj  

GENERAL HOSPITAL, VIENNA. [PDF]

The Lancet
n ...
openaire   +2 more sources

Assessment of Obstetric and Neonatal Health Services in Developing Country Health Facilities [PDF]

, 2013
OBJECTIVE: To describe the staffing and availability of medical equipment and medications and the performance of procedures at health facilities providing maternal and neonatal care at African, Asian, and Latin American sites participating in a ...
Albert Manasyan, Ana Garces, Archana Patel, Bhala Kodkany, Edward Liechty, Elizabeth McClure, Elwyn Chomba, Fabian Esamai, Fernando Althabe, Janet Moore, Jose Belizan, K. Hambidge, Linda Wright, Marion Koso-Thomas, null null, Omrana Pasha, Patricia Hibberd, Pierre Buekens, Richard Derman, Robert Goldenberg, Sarah Saleem, Shivaprasad Goudar, Waldemar Carlo   +22 more
core   +1 more source

Raphin‐1 mediates the survival and sensitivity to radiation of pediatric‐type diffuse high‐grade glioma via phosphorylated eukaryotic initiation factor 2α‐dependent and ‐independent processes

Molecular Oncology, EarlyView.
Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan, Moshe Leitner, Amos Toren, Shoshana Paglin, Michal Yalon   +4 more
wiley   +1 more source

Comparison of Job Stress, Hardness, and Burnout of Nurses between Advanced general Hospitals and general Hospitals

, 2012
This study was conducted to compare nurses` job stress, hardness and burnout between general hospitals and advanced general hospitals. Data were obtained through structured questionnaires from 394 nurses(general 198, upgrade general 196) in the C and S ...
J. Choi, Seungmi Park
semanticscholar   +1 more source

Effects of ownership, subsidization and teaching activities on hospital costs in Switzerland [PDF]

This paper explores the cost structure of Swiss hospitals, focusing on differences due to teaching activities and those across different ownership and subsidization types.
Massimo Filippini, Medhi Farsi
core