Results 121 to 130 of about 65,372 (285)

Task co‐use and product improvement: An organization design perspective

Strategic Management Journal, EarlyView.
Abstract Research Summary Co‐using tasks—using the same task to produce more than one product—promises economies of scope. However, task co‐use also ties products together, changing a firm's task network by introducing cross‐product interdependencies. In light of these interdependencies, we identify an unrecognized downside of task co‐use for product ...
Johanna Glauber, Tobias Kretschmer
wiley   +1 more source

Cell Culture Substrate Variation Alters Extracellular Vesicle Biogenesis Without Affecting Non‐Coding Repeat RNA Profile

Small, EarlyView.
Cell culture biomechanical conditions influence extracellular vesicles (EVs) production in patient‐derived pancreatic adenocarcinoma (PDAC) cell lines. When grown in 3D conformation and in hydrogels with lower elasticity (0.5kPA), PDAC cells produce higher numbers of EVs, compared with cells grown in 2D on classic cell culture plastic.
Sara I. Veiga, Rebecca L. Porter, Berent Aldikacti, Uma K. Paithankar, Kate Calhoun, Eric Tai, Vishal Thapar, Jillian F. Wise, David T. Ting, Shannon L. Stott   +9 more
wiley   +1 more source

Triboelectric Capacitance Supplementation in Energy Storage Composites with Functionalized Carbon Fiber Electrodes

Small, EarlyView.
Triboelectric contact electrification evaluation between structural supercapacitor layers using surface‐functionalized carbon fiber electrodes. Electrospun nanofiber separators can aid in capacitance augmentation by leveraging the contact electrification effect of dissimilar materials.
Žan Simon, Bhagya Dharmasiri, Ronald T. Leon, Ben Newman, Fatemeh Mokhtari, Piers Coia, Elmer S. Austria Jr., Behnam Akhavan, Peter C. Sherrell, Amanda V. Ellis, Russell J. Varley, Luke C. Henderson   +11 more
wiley   +1 more source

Pharmaceuticals Delivery in Ireland. Getting a Bigger Bang for the Buck [PDF]

Ireland
Brick, Aoife, Gorecki, Paul K., Lyons, Seán, Nolan, Anne   +3 more
core  

Renovating Neural Networks With Viral‐Mediated Gene Transfer From A Tissue Contacting Matrix Mimic

Small, EarlyView.
Fmoc‐DDIKVAV self‐assembling peptidemediated delivery of AAV‐BDNF significantly enhances neuroprotection in the striatum of a mouse model compared with AAV‐BDNF injection alone. This synergistic integration of biomaterial scaffolding and gene therapy holds substantial promise for slowing the progression of neurodegenerative diseases such as Huntington ...
Shiva Soltani Dehnavi, Negar Mahmoudi, Yi Wang, Samuel Cheeseman, Rita Ferreira, Ross D. Hannan, Leszek Lisowski, Vincent S. J. Craig, Niamh Moriarty, Clare L. Parish, Richard J. Williams, David R. Nisbet   +11 more
wiley   +1 more source

Application of a discrete event simulator for healthcare processes [PDF]

, 2015
Casier, Gregory, Casier, Koen, Van Ooteghem, Jan, Verbrugge, Sofie   +3 more
core   +1 more source

Lifecycle‐Based Governance to Build Reliable Ethical AI Systems

Systems Research and Behavioral Science, EarlyView.
ABSTRACT Artificial intelligence (AI) systems represent a paradigm shift in technological capabilities, offering transformative potential across industries while introducing novel governance and implementation challenges. This paper presents a comprehensive framework for understanding AI systems through three critical dimensions: trustworthiness ...
Maikel Leon
wiley   +1 more source

Treatments for renal cell carcinoma: NICE Pilot Treatment Pathways Appraisal

Health Technology Assessment
Background The National Institute for Health and Care Excellence is piloting a new approach to evaluating health technologies, which takes into consideration the full treatment pathway for a condition.
Dawn Lee, Madhusubramanian Muthukumar, Alan Lovell, Caroline Farmer, Darren Burns, Justin Matthews, Helen Coelho, Brian O’Toole, Laura A Trigg, Tristan M Snowsill, Maxwell S Barnish, Thalia Nikoglou, Amanda Brand, Zain Ahmad, Ahmed Abdelsabour, Louise Crathorne, Sophie Robinson, Edward CF Wilson, GJ Melendez-Torres   +18 more
doaj   +1 more source

Erving Goffman at 100: A Chameleon Seen as a Rorschach Test within a Kaleidoscope

Symbolic Interaction, EarlyView.
The 100th anniversary of Erving Goffman's birth was in 2022. Drawing on his work, the Goffman archives, the secondary literature, and personal experiences with him and those in his university of Chicago cohort, I reflect on some implications of his work and life, and the inseparable issues of understanding society.
Gary T. Marx
wiley   +1 more source

Advancing Model‐Based Systems Engineering in the Development of Naval Vessel Systems Architecture

Systems Engineering, EarlyView.
ABSTRACT The increasing complexity of modern naval vessels due to technological advancements poses challenges for early‐stage ship design (ESSD). Developing well‐defined system architectures and adopting systems engineering approaches are essential to address these challenges.
Vasileios Sideris, Zacharias P. Oikonomou, Sam Gerené, Austin A. Kana   +3 more
wiley   +1 more source