Results 101 to 110 of about 65,280 (309)
Abstract Background Short bowel syndrome (SBS) is a chronic condition requiring parenteral nutrition (PN) support and multidisciplinary management. However, disparities in access to care and standardized treatment pathways, in addition to economic burden, remain considerable for patients.
Deborah Kuk +7 more
wiley +1 more source
Clinical Characteristics and Progression of Pachychoroid and Conventional Geographic Atrophy
Purpose: To elucidate the clinical characteristics and progression rates of pachychoroid and conventional geographic atrophy (GA). Design: Retrospective, multicenter, observational study.
Yukiko Sato, MD +17 more
doaj +1 more source
• Advanced large language models exhibited superior diagnostic accuracy compared to clinicians, particularly for rare diseases, with Claude‐3.5 Sonnet and o1‐preview demonstrating the highest consistency between query iterations. ABSTRACT Importance Rigorous evaluation of large language models (LLMs) in pediatric diagnosis using authentic clinical ...
Cristian Launes +12 more
wiley +1 more source
Urinary Collagen Peptides Predict Mortality
ABSTRACT Organ fibrosis caused by the presence of excessive extracellular matrix (ECM) is related to mortality. Urinary peptide signatures were reported to be predictive of death in SARS‐CoV‐2 and chronic kidney disease. Such signatures were composed for 68% of collagen fragments.
Maria Frantzi +15 more
wiley +1 more source
Counting Change: Measuring Health Care Prices, Costs, and Spending [PDF]
Considers the accuracy and utility of current data on the determinants of healthcare costs, distorting factors that make measuring the costs of healthcare delivery difficult, the benefits of cost and spending measurement, and efforts to develop ...
core
ABSTRACT Background The management of intermediate‐risk early prostate cancer (PCa) is challenging due to the difficulty in distinguishing indolent from aggressive tumors. This study explores the association between genomic alterations and the tumor and its microenvironment (TME) and implications for disease progression. Methods We performed multi‐omic
William Lautert‐Dutra +13 more
wiley +1 more source
Advancing pharmacometrics in Africa—Transition from capacity development toward job creation
Abstract Trained pharmacometricians remain scarce in Africa due to limited training opportunities, lack of a pharmaceutical product development ecosystem, and emigration to high‐income countries. The Applied Pharmacometrics Training (APT) fellowship program was established to address these gaps and specifically foster job creation for talent retention.
Goonaseelan (Colin) Pillai +10 more
wiley +1 more source
Abstract Background Osteoarthritis (OA) causes chronic pain and reduces welfare in dogs. Standard treatments may be inadequate or associated with adverse effects, prompting investigation of alternative therapies. Transcutaneous electrical nerve stimulation (TENS) is a non‐pharmacological pain management method, but evidence for its efficacy in canine ...
Anja Pedersen +5 more
wiley +1 more source
ABSTRACT The disinheritance of a firstborn son accustomed to the privileges of exclusion has for centuries been a dramatic event for families, especially if the decision was taken by a woman, the son's own mother. Very few dared to do so, because it symbolised a break with the notion of virtuous, compassionate motherhood; it represented a failure to be
Mariela Fargas Peñarrocha
wiley +1 more source

