Results 101 to 110 of about 65,280 (309)

Quality of life and healthcare resource utilization among adult patients with short bowel syndrome: A mixed‐methods study leveraging an integrated database

open access: yesNutrition in Clinical Practice, EarlyView.
Abstract Background Short bowel syndrome (SBS) is a chronic condition requiring parenteral nutrition (PN) support and multidisciplinary management. However, disparities in access to care and standardized treatment pathways, in addition to economic burden, remain considerable for patients.
Deborah Kuk   +7 more
wiley   +1 more source

Clinical Characteristics and Progression of Pachychoroid and Conventional Geographic Atrophy

open access: yesOphthalmology Science
Purpose: To elucidate the clinical characteristics and progression rates of pachychoroid and conventional geographic atrophy (GA). Design: Retrospective, multicenter, observational study.
Yukiko Sato, MD   +17 more
doaj   +1 more source

Large‐language‐models for pediatric diagnosis: Performance evaluation using real‐world clinical notes from common and rare cases

open access: yesPediatric Investigation, EarlyView.
• Advanced large language models exhibited superior diagnostic accuracy compared to clinicians, particularly for rare diseases, with Claude‐3.5 Sonnet and o1‐preview demonstrating the highest consistency between query iterations. ABSTRACT Importance Rigorous evaluation of large language models (LLMs) in pediatric diagnosis using authentic clinical ...
Cristian Launes   +12 more
wiley   +1 more source

Urinary Collagen Peptides Predict Mortality

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Organ fibrosis caused by the presence of excessive extracellular matrix (ECM) is related to mortality. Urinary peptide signatures were reported to be predictive of death in SARS‐CoV‐2 and chronic kidney disease. Such signatures were composed for 68% of collagen fragments.
Maria Frantzi   +15 more
wiley   +1 more source

Counting Change: Measuring Health Care Prices, Costs, and Spending [PDF]

open access: yes, 2012
Considers the accuracy and utility of current data on the determinants of healthcare costs, distorting factors that make measuring the costs of healthcare delivery difficult, the benefits of cost and spending measurement, and efforts to develop ...

core  

Impact of Genomic Mutations on the Transcriptional Pathways and Tumor Microenvironment Landscape of Localized Early Prostate Cancer

open access: yesThe Prostate, EarlyView.
ABSTRACT Background The management of intermediate‐risk early prostate cancer (PCa) is challenging due to the difficulty in distinguishing indolent from aggressive tumors. This study explores the association between genomic alterations and the tumor and its microenvironment (TME) and implications for disease progression. Methods We performed multi‐omic
William Lautert‐Dutra   +13 more
wiley   +1 more source

Advancing pharmacometrics in Africa—Transition from capacity development toward job creation

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 407-419, March 2025.
Abstract Trained pharmacometricians remain scarce in Africa due to limited training opportunities, lack of a pharmaceutical product development ecosystem, and emigration to high‐income countries. The Applied Pharmacometrics Training (APT) fellowship program was established to address these gaps and specifically foster job creation for talent retention.
Goonaseelan (Colin) Pillai   +10 more
wiley   +1 more source

Effect of transcutaneous electrical nerve stimulation on physical activity and pain evaluation in osteoarthritic dogs

open access: yesVeterinary Record, EarlyView.
Abstract Background Osteoarthritis (OA) causes chronic pain and reduces welfare in dogs. Standard treatments may be inadequate or associated with adverse effects, prompting investigation of alternative therapies. Transcutaneous electrical nerve stimulation (TENS) is a non‐pharmacological pain management method, but evidence for its efficacy in canine ...
Anja Pedersen   +5 more
wiley   +1 more source

Mothers against the natural order: Gender representations and desertion of identities in the drama of disinheriting a son in eighteenth‐century Barcelona  

open access: yesGender &History, EarlyView.
ABSTRACT The disinheritance of a firstborn son accustomed to the privileges of exclusion has for centuries been a dramatic event for families, especially if the decision was taken by a woman, the son's own mother. Very few dared to do so, because it symbolised a break with the notion of virtuous, compassionate motherhood; it represented a failure to be
Mariela Fargas Peñarrocha
wiley   +1 more source

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