Results 41 to 50 of about 65,372 (285)

Strawberry Notch 1 Acts as a Transcriptional Regulator Driving Oncogenic Programs in Liver Carcinogenesis

open access: yesAdvanced Science, EarlyView.
This study reports that SBNO1 protein is upregulated in several cancer entities. SBNO1 protein interacts with the basal transcription factor TFIID via TAF4, enabling its recruitment to transcription start sites and the modulation of target gene expression.
Sarah Fritzsche   +21 more
wiley   +1 more source

Adenylyl Cyclase 8 in Dorsal CA1 Neurons Prevents Depressive‐Like Behaviors by Maintaining Neuronal Excitability and Glutamatergic Neurotransmission Through TIP39‐PTH2R Signaling

open access: yesAdvanced Science, EarlyView.
Depression, a prevalent neuropsychiatric disorder with unclear pathogenesis, involves dysfunctional adenylyl cyclase 8 (Adcy8) as a key risk factor. Chronic stress selectively reduces Adcy8 expression in the dorsal CA1 (dCA1) neurons. Depletion of Adcy8 in dCA1 excitatory neurons induces depressive‐like behaviors by impairing neuronal excitability and ...
Zi‐Jie Liu   +14 more
wiley   +1 more source

Evaluating a Widely Implemented Proprietary Deterioration Index Model Among Hospitalized COVID-19 Patients [PDF]

open access: yes, 2020
ABSTRACTIntroductionThe Epic Deterioration Index (EDI) is a proprietary prediction model implemented in over 100 U.S. hospitals that was widely used to support medical decision-making during the COVID-19 pandemic. The EDI has not been independently evaluated, and other proprietary models have been shown to be biased against vulnerable populations ...
Karandeep Singh   +14 more
openaire   +2 more sources

Evaluating a Widely Implemented Proprietary Deterioration Index Model among Hospitalized Patients with COVID-19

open access: yesAnnals of the American Thoracic Society, 2021
Rationale: The Epic Deterioration Index (EDI) is a proprietary prediction model implemented in over 100 U.S. hospitals that was widely used to support medical decision-making during the coronavirus disease (COVID-19) pandemic. The EDI has not been independently evaluated, and other proprietary models have been shown to be biased against vulnerable ...
Karandeep Singh   +14 more
openaire   +2 more sources

The Growing Imbalance: Recent Trends in U.S. Postsecondary Education Finance [PDF]

open access: yes, 2008
Compares trends at public, private, and research institutions in enrollment, revenues, and spending as well as their effect on bottom lines; analyzes widening disparities; and considers implications for improving the affordability of higher ...
Colleen M. Lenihan   +2 more
core  

PEDOT:PSS—A Key Material for Bioelectronics

open access: yesAdvanced Science, EarlyView.
PEDOT:PSS ‐ Poly(3,4‐ethylenedioxythiophene) polystyrene sulfonate ‐ is typically processed from water dispersions to form multifunctional and multidimensional constructs with tunable electronic and ionic conductivity. Throught processing engineering, PEDOT:PSS is intergrated in bioelectronic devices that operate efficiently in physiological conditions
Alan Eduardo Ávila Ramírez   +5 more
wiley   +1 more source

How to Develop IoT Cloud e-Health Systems Based on FIWARE: A Lesson Learnt

open access: yesJournal of Sensor and Actuator Networks, 2019
Nowadays, the penetration of sensors and actuators in different application fields is revolutionizing all aspects of our daily life. One of the major sectors that is taking advantage of such cutting-edge cheap smart devices is healthcare. In this context,
Antonio Celesti   +7 more
doaj   +1 more source

GlycoChat Uncovers Glycan–Lectin Circuits in the Tumor Microenvironment of Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
Aberrant glycosylation drives cancer progression, yet its role in the tumor microenvironment remains unclear. We developed GlycoChat to map glycan–lectin circuits at single‐cell resolution. We discovered that cancer cells induce immunosuppressive macrophage differentiation and impair phagocytosis through interactions with CLEC10A and SIGLEC3 ...
Dinh Xuan Tuan Anh   +8 more
wiley   +1 more source

Patients\u27 Rights to Access their Medical Records: An Argument for Uniform Recognition of a Right of Access in the United States and Australia [PDF]

open access: yes, 1997
This Note addresses the issue of a patient\u27s right to access her own medical records in the United States and Australia. Part I discusses the background of a right of patient access to medical records through case law in the United States.
Rosenman, Hayley
core   +1 more source

A Wireless, Battery‐Free Artificial Throat Patch with Deep Learning for Emotional Speech Recognition

open access: yesAdvanced Science, EarlyView.
In this work, Xu and co‐workers develop a wireless, battery‐free artificial throat patch system (ATPS) consisting of a carbon nanotube‐based thin‐film strain sensor and a miniaturized flexible printed circuit board, to enable real‐time sensing of throat signals.
Bingxin Xu   +10 more
wiley   +1 more source

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