Results 121 to 130 of about 158,436 (189)

Human phase‐I metabolism of three synthetic cannabinoids bearing a cumyl moiety and a cyclobutyl methyl or norbornyl methyl tail: Cumyl‐CBMEGACLONE, Cumyl‐NBMEGACLONE, and Cumyl‐NBMINACA

Drug Testing and Analysis, EarlyView.
The human phase‐I metabolism of three SCRAs bearing a cumyl moiety and a CBM or NBM tail, based on LC‐qToF‐MS data of authentic urine specimens. Abstract Synthetic cannabinoid receptor agonists (SCRAs) continue to show high prevalence on the new psychoactive substances drug market.
Arianna Giorgetti, Pietro Brunetti, Belal Haschimi, Benedikt Pulver, Jennifer Paola Pascali, Jan Riedel, Volker Auwärter   +6 more
wiley   +1 more source

Associations Between Self‐Reported Cocaine Use Patterns and Cocaine and Its Metabolites in Hair: Implications for Clinical and Forensic Practices

Drug Testing and Analysis, EarlyView.
This study demonstrates that concentrations of cocaine and its main metabolites in hair reliably predict an individual's actual intensity of cocaine use and effectively differentiate between dependent and non‐dependent users. ABSTRACT In forensic toxicology, it has been debated if hair testing allows an estimation of the intensity of cocaine use—an ...
Simon Grison, Lydia Johnson‐Ferguson, Matthias Vonmoos, Markus R. Baumgartner, Boris B. Quednow   +4 more
wiley   +1 more source

Analytical and Pharmacological Characterization of 1‐(Furan‐2‐Carbonyl)‐LSD (1F‐LSD) and Comparison With 1‐(Thiophene‐2‐Carbonyl)‐LSD (1T‐LSD)

Drug Testing and Analysis, EarlyView.
The novel lysergamide 1‐(furan‐2‐carbonyl)‐LSD (1F‐LSD) was analytically characterized. 1F‐LSD showed LSD‐like activity in vivo similar to 1‐(thiophene‐2‐carbonyl)‐LSD (1T‐LSD) used for comparison. Administration studies in mice and LC–MS analysis revealed that 1F‐LSD served as a prodrug.
Simon D. Brandt, Pierce V. Kavanagh, Sarah Gare, Simon P. Elliott, Alexander Stratford, Adam L. Halberstadt   +5 more
wiley   +1 more source

Superintendents of psychiatric hospitals. [PDF]

BMJ, 1976
openaire   +3 more sources

Infant Death due to Cannabis Ingestion

Drug Testing and Analysis, EarlyView.
ABSTRACT A child died in the emergency room of a local hospital a few hours after ingesting a substance the color of cork and the consistency of earth. At home, a modest amount of resinous substance was found. At the hospital, the child exhibited alterations in walking, balance, and consciousness.
Donata Favretto, Antonello Cirnelli, Roberto Pertile, Raffaella Stimamiglio, Clara Cestonaro, Oriana Cuman, Anna Pagliaro, Fabio Mattiazzi, Cristina Basso, Maddalena Galeazzi   +9 more
wiley   +1 more source

Health Economic Evaluation of Cognitive‐Behavioral Therapy for Adolescents With Binge‐Eating Disorder in Germany

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective To determine the cost‐effectiveness of cognitive‐behavioral therapy (CBT) for adolescents with binge‐eating disorder (BED), focusing on the costs per binge‐free episode and per quality‐adjusted life year (QALY) gained in comparison to a waitlist (WL) control group.
Nicolas Pardey, Ricarda Schmidt, Jan Zeidler, Anja Hilbert   +3 more
wiley   +1 more source

Consensus‐Based Recommendations for Yoga as Adjunct Therapy in Eating Disorder Treatment: A Delphi Study

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective This study aimed to develop consensus‐based statements, combining the expertise of eating disorder (ED) clinicians and yoga instructors, on key considerations for applying yoga for individuals with anorexia nervosa, bulimia nervosa, and binge‐eating disorder.
Eleanor Trethewey, Subhadra Evans, Shane McIver, Michael de Manincor, Janani Janakiraman, Arvind V. Iyer, Melissa O'Shea   +6 more
wiley   +1 more source

Impact of the COVID‐19 Pandemic on the Incidence of Anorexia and Bulimia Nervosa in Dutch Primary Care

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective This study examined the impact of the COVID‐19 pandemic on incidence rates of anorexia nervosa (AN) and bulimia nervosa (BN) in Dutch primary care by comparing pre‐pandemic (2015–2019) and in‐pandemic (2020–2022) periods. We hypothesized that the incidence of AN and BN would increase during the pandemic.
K. Meier, D. van Hoeken, C. C. M. Kager, A. E. van Eeden, A. J. Oldehinkel, H. W. Hoek   +5 more
wiley   +1 more source

eBEfree: Combining Psychoeducation, Mindfulness, and Self‐Compassion in an App‐Based Psychological Intervention to Manage Binge‐Eating Symptoms: A Randomized Controlled Trial

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective To develop and test the effectiveness of the eBEfree program, a 12‐session app‐based version of a previously tested psychological intervention (BEfree) that combines psycho‐education, self‐compassion, mindfulness, and Acceptance and Commitment Therapy to reduce binge‐eating symptoms.
Hugo Senra, Cristiana Duarte, Sérgio A. Carvalho, Luís Simões, Cláudia Ferreira, Lara Palmeira, Marcela Matos, Marina Cunha, Paula Castilho, Bruno Sousa, Luis Cordeiro, José Pinto‐Gouveia   +11 more
wiley   +1 more source

Premature Mortality in Patients With Anorexia Nervosa: A Matched Cohort Study of Cause of Death

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective To determine the extent to which anorexia nervosa is associated with premature mortality. Method We carried out a matched cohort study of 7332 male and female patients with anorexia nervosa and 73,215 patient controls who were admitted between 1989 and 2023 in hospital centers of Quebec, Canada. We tracked the patients longitudinally
Nathalie Auger, Mimi Israël, Howard Steiger, Nancy Low, Nicholas Chadi, Émilie Brousseau, Aimina Ayoub, Gabriel Côté‐Corriveau   +7 more
wiley   +1 more source