Results 121 to 130 of about 280,108 (312)

Thematic series CAPMH “Forensic Child and Adolescent Psychiatry and Mental Health 2017”

open access: yesChild and Adolescent Psychiatry and Mental Health, 2018
Cyril Boonmann   +2 more
doaj   +1 more source

Cultural representations of mental illness in contemporary Japan [PDF]

open access: yes, 2014
This paper presents the results of a research project aimed at studying the cultural representations of mental illness and related interventions models in contemporary Japan, and providing the basis for a comparison between Japanese and Italian mental ...
Bucci, Fiorella
core  

Distinct Biotypes of Visual Perception in Major Depressive Disorder

open access: yesAdvanced Science, EarlyView.
In a discover dataset (272 acute MDD patients), this work identifies a novel depression biotype characterized by impaired visual motion perception, using machine learning clustering. An independent dataset confirms the robustness of this biotype through cross‐validation and demonstrates its generalizability.
Zhuoran Cai   +13 more
wiley   +1 more source

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

open access: yesAdvanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters   +12 more
wiley   +1 more source

Supportive Housing in Illinois: A Wise Investment [PDF]

open access: yes, 2009
This study reports on 177 supportive housing residents around Illinois, comparing their use of publicly-funded services two years before entering supportive housing to two years after entry.
Alyssa Nogaski   +3 more
core  

Kinsenoside Targets IDH1 to Restore Microglial Immune‐Metabolic Homeostasis for Alzheimer's Disease Therapy

open access: yesAdvanced Science, EarlyView.
Dysregulated TCA cycle contributes to Alzheimer's disease (AD) pathogenesis. Here, we show that microglial isocitrate dehydrogenase 1 (IDH1) is a critical driver. Elevated IDH1 disrupts citrate metabolism and mitochondrial function, exacerbating AD pathology.
Qianqian Li   +13 more
wiley   +1 more source

Mental Health Challenges Among Psychiatric Healthcare Workers During the COVID-19 Pandemic: Insights from Türkiye and Future Directions

open access: yesNeuropsychiatric Investigation
Objective: This study aimed to examine the psychological challenges faced by mental health professionals working in COVID-19-specific psychiatric inpatient units compared to those working in regular (nonCOVID) psychiatric inpatient settings ...
Mine Ergelen   +7 more
doaj   +1 more source

Families, insanity and the psychiatric institution in Australia and New Zealand, 1860-1914 [PDF]

open access: yes, 2006
International historians have begun to challenge the view that the nineteenth-century psychiatric hospital was a place of horrors and custody, and have shown that families were sometimes intimate with the institutions of the past, often participating in ...
Coleborne, Catharine
core   +1 more source

Paternal Caffeine Exposure Programs Offspring Stress Vulnerability via Sperm Dlk1‐Dio3 Imprinting‐Directed Remodeling of a Novel Neural Circuit

open access: yesAdvanced Science, EarlyView.
The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu   +10 more
wiley   +1 more source

“Membrane‐Guided” Repair Strategy: Precision Delivery of GGT1 Degrader for Targeted Repair and Regeneration of Spinal Cord Neurons

open access: yesAdvanced Science, EarlyView.
This study confirms that GGT1 is a key driver of neuronal ferroptosis following spinal cord injury. We developed NSCm@EA, a biomimetic delivery system coated with neural stem cell membranes, for precise delivery of enocyanin to injured neurons. By combining targeted delivery with ubiquitination degradation mechanisms, this system promotes MGRN1 ...
Tao Yang   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy