Results 91 to 100 of about 1,515,540 (311)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Public-private partnerships for hospitals

open access: yesBulletin of the World Health Organization, 2006
While some forms of public-private partnerships are a feature of hospital construction and operation in all countries with mixed economies, there is increasing interest in a model in which a public authority contracts with a private company to design ...
Martin McKee, Nigel Edwards, Rifat Atun
doaj  

Bureauphobia in Public Hospitals of Qom, Iran

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2022
Background and Objectives: Bureauphobia in the public sector doubts the direct effect of good services on people’s trust. Addressing bureauphobia in public hospitals can be an attempt for increasing trust in the public sector, in addition to improving ...
Ahmad Rahbar   +4 more
doaj  

SHEFFIELD PUBLIC HOSPITAL. [PDF]

open access: yesThe Lancet, 1884
null Thomas, null Thorpe
openaire   +3 more sources

Borrowing for hospitalization in India [PDF]

open access: yes
Borrowing to cover hospital costs is a major concern in developing countries, like India, as it may push households into despairs of poverty and indebtedness. The present study examines factors that lead to borrowing for hospitalization in case of Indian
Pal, Rama
core   +1 more source

Transmission of severe acute respiratory syndrome in dynamical small-world networks

open access: yes, 2004
The outbreak of severe acute respiratory syndrome (SARS) is still threatening the world because of a possible resurgence. In the current situation that effective medical treatments such as antiviral drugs are not discovered yet, dynamical features of the
A. L. Lloyd   +23 more
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Project 25: Housing the Most Frequent Users of Public Services Among the Homeless [PDF]

open access: yes, 2015
The purpose of Project 25 is to investigate whether providing permanent housing with intensive individualized support, coupled with an identified, "Medical Home," can realize a significant reduction in the use and cost of public services.
Lynn Reaser
core  

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

PRODUCTIVITY INDICATORS IN PUBLIC HOSPITALS

open access: yesVisión de Futuro, 2017
The public hospital is the great receiver par excellence in what refers to traumatized, but that excellence seems to fade in the face of poor building conditions and inefficient processes, product, perhaps, of the imposing current message that states ...
Medina, Orlando Francisco   +1 more
doaj  

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