Results 91 to 100 of about 614,763 (265)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Comparative study of the relationship between job satisfaction and burnout among Nurses in Public and Private Hospitals in Shiraz City in 2012

بیمارستان, 2015
Background: ‌ Based on increasing the privatization in hospitals, conducting researches in various fields of private hospitals and comparison with public hospitals is greatly felt.This study aimed at investigating the relationship between job ...
hojat habibi, Alireza mooghali, Foruzan habibi, mehrdad ahmadi   +3 more
doaj  

PREVALENCE OF CESARIAN DELIVERY AND ASSOCIATED FACTORS AMONG MOTHERS WHO GAVE BIRTH AT PUBLIC HOSPITALS IN ETHIOPIA: A CROSS-SECTIONAL STUDY

JPH RECODE (Journal of Public Health Research and Community Health Development)
Background: Caesarean delivery is a procedure used to save a mother’s and foetus’s lives when the labour situation becomes complicated. However, a wrong decision can substantially increase the rates of morbidity and mortality of the woman and the fetus ...
Abdulahi Mohamud Yusuf, Abdifetah Abdulahi Sheik, Mohamud Hussein Ali, Hussen Abdi Hassen   +3 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Integrated public town hospitals

International Journal of Integrated Care, 2013
Ilhami Unluoglu, Ugur Bilge
doaj   +3 more sources

Single-operator cholangioscopy monitoring of a remaining bile duct after congenital choledochal cyst surgery: a case report with an innovative approach

VideoGIE, 2022
Antoine Martin, MD, Paul Rivallin, MD, Frédérique Maire, MD, Diane Lorenzo, MD, Jaïs Bénédicte, MD, Alain Aubert, MD, Abdellah Hedjoudje, MD, Frédéric Prat, MD, PhD   +7 more
doaj   +1 more source

Sleep apnea and daytime sleepiness in police officers from Kerala, India

BMC Public Health
Background Globally, poor sleep is a significant public health problem. Healthy sleep is important for physical and mental well-being, particularly for individuals who work in environments with shift schedules. However, this issue has not been adequately
G. K. Mini, Krishna S. Sangeeth, Gopinathan Bhaskaran Gopika, V. M. Anjana, Pillai Anand Marthanda, Aswathy Sreedevi, Pillai A. Marthanda, Vilma Irazola   +7 more
doaj   +1 more source