Results 71 to 80 of about 1,515,540 (311)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Ownership Form and Trapped Capital in the Hospital Industry [PDF]

open access: yes
Over the past 20 years, demand for acute care hospital services has declined more rapidly than has hospital capacity. This paper investigates the extent to which the preponderance of the nonprofit form in this industry might account for this phenomenon ...
Daniel Kessler   +2 more
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Public problems: private solutions? Short-term contracting of inpatient hospital care [PDF]

open access: yes
Executive summary Public patients are routinely being treated in Australian private hospitals. Some jurisdictions have large-scale, planned programs where private or not-for-profit hospitals are contracted by the public sector to treat public inpatients
Anne-Marie Boxall   +2 more
core  

A Comparison of Quality of Care in Critical Access Hospitals and Other Rural Hospitals [PDF]

open access: yes, 2014
Purpose: The United States has about 2100 rural hospitals. Approximately 1300 are Critical Access Hospitals (CAHs) with 25 beds or less. CAHs receive cost-based reimbursement through the federal Flex program with the goal to improve quality and access to
Baernholdt, Marianne   +4 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Produtividade em hospitais de acordo com alguns indicadores hospitalares

open access: yesRevista de Saúde Pública
Dos equipamentos utilizados pela área de saúde para provisão de cuidados assistenciais, os hospitais certamente são preferidos tanto pela população como também pelos profissionais da área. Isto ocorre devido às facilidades e segurança que oferecem face à
Olímpio J. Nogueira V. Bittar
doaj  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Simple and Combined Relationships between Informal Learning and Job Satisfaction among Nurses in Governmental Teaching Hospitals of Isfahan City

open access: yesمدیریت اطلاعات سلامت, 2014
Introduction: Organizations are the major institutions in the world that their efficiency is dependent on human resources and human performance. Positive attitude towards the job is an important target in any organization to improve the human resources ...
Mohammad Ali Nadi   +2 more
doaj  

Analysis of hospital service areas in Istanbul [PDF]

open access: yes
After 1950's, the rapid expansion of Istanbul has created tremendous demand for new public facilities as well as the need for evaluation of existing facilities.
M. Aykut Sadi, Vedia Dokmeci
core  

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