Results 61 to 70 of about 1,515,540 (311)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Prevalence and associated risk factors of hypertension among tribal population in Thrissur District: A cross-sectional study in South India

Clinical Epidemiology and Global Health
Introduction: Hypertension is the major cause of premature death worldwide. There are disparities in the prevalence of hypertension across cultural groups.
M.G. Aswin, Marthanda Pillai Anand, Prabhakar Jessy, Jinbert Lordson A, Job PJ. Jibin, A.P. Nisam, M.S. Adarsh, Fathima Nazar Asmi, G.K. Mini   +8 more
doaj   +1 more source

Putting on the brakes : certificate of need regulations try to steer health-care supplies, but it's hard to keep them from fishtailing [PDF]

Medical care, Cost of ; Hospitals - Economic aspects ; Public ...
Charles Gerena
core  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Hospitals, Managed Care, and the Charity Caseload in California [PDF]

Many observers have blamed HMOs for increasing financial pressures on private hospitals and causing them to cut back on the provision of charity care. We examine this issue using data on all hospital discharges in California between 1988 and 1996.
Janet Currie, John Fahr
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Comparative assessment of rational use of drugs in public and private hospital pharmacies: a multicenter cross-sectional study using INRUD/WHO prescribing indicators

Journal of Pharmaceutical Policy and Practice
Background Specific actions to promote the RUD in public and private hospitals are highly needed. The current study aimed to assess RUD based on World Health Organization (WHO) prescribing indicators in selected public and private hospitals in Khartoum ...
Adil A. Mahmoud, Asim Ahmed Elnour, Ali Awadallah Saeed, Vineetha Menon, Shereen A. M. Elhag, Omkalthoum Fathi G, Mohamed Ayoup M, Hussam Abdulhadi M A, Ahmed Sameer E, Mohamed Tahaa E, Semira Abdi Beshir, Nadia Al Mazrouei, Sami Fatehi Abdalla, Fahad T. Alsulami, Yousef Saeed Alqarni, Abuelnor Mohammed   +15 more
doaj   +1 more source

Assessing Concordance Across Nonprofit Hospitals' Public Reporting on Housing as a Community Health Need in the Era of the Affordable Care Act. [PDF]

J Public Health Manag Pract, 2022
Chen KL, Chen K, Holaday LW, Lopez L.
europepmc   +1 more source

Measuring Hospital Efficiency through Data Envelopment Analysis when Policy-makers’ Preferences Matter. An Application to a sample of Italian NHS hospitals [PDF]

In this paper we show how both the choice of specific constraints on input and output weights (in accordance with health care policy-makers’ preferences) and the consideration of exogenous variables outside the control of hospital management (and linked ...
Dino Rizzi, Vincenzo Rebba
core  

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source